{"id":"W2588682466","doi":"10.1095/biolreprod.116.141267","title":"The ubiquitous isoform of Na/K-ATPase (ATP1A1) regulates junctional proteins, connexin 43 and claudin 11 via Src-EGFR-ERK1/2-CREB pathway in rat Sertoli cells†","year":2017,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sertoli cell; Ouabain; Claudin; Connexin; Cell biology; Biology; Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Internal medicine; Gene isoform; Endocrinology; Gap junction; Tight junction; Chemistry; Intracellular; Biochemistry; Sodium; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656024,0.000231811,0.0003071539,0.0002491617,0.0001676035,0.0002189866,0.000174924,0.0002134467,0.001148753],"category_scores_gemma":[0.00007855751,0.0001898247,0.0002695673,0.0001895418,0.0001588607,0.0002813291,0.0001243576,0.0003841783,0.0003193613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001635419,"about_ca_system_score_gemma":0.0001986869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001189495,"about_ca_topic_score_gemma":0.00199427,"domain_scores_codex":[0.999899,0.00001405397,0.000009035328,0.00001857404,0.00003352936,0.00002580876],"domain_scores_gemma":[0.9999032,0.00001127517,0.00002940166,0.000007162164,0.00001842283,0.00003041603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006658239,0.00001549441,0.00017453,0.0000452643,0.000003813162,0.00003837628,0.00001795483,0.00001610649,0.9991067,0.00003762443,0.00002052507,0.0004571029],"study_design_scores_gemma":[0.0000290579,0.0004670722,0.02799097,0.00000879658,0.00005002315,0.0004783099,0.00009954309,0.001131444,0.96706,0.00003983206,0.002637612,0.000007354389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930559,0.003959086,0.001683759,0.0001017174,0.00003120102,0.00001688432,0.0003084711,0.00005858799,0.0007843571],"genre_scores_gemma":[0.9922493,0.002133683,0.001741619,0.00003552518,0.00001947028,0.00002843619,0.0007502732,0.00001307629,0.003028522],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001189495,"threshold_uncertainty_score":0.003843009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01036735693037872,"score_gpt":0.2383275261463746,"score_spread":0.2279601692159959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}