{"id":"W2588682466","doi":"10.1095/biolreprod.116.141267","title":"The ubiquitous isoform of Na/K-ATPase (ATP1A1) regulates junctional proteins, connexin 43 and claudin 11 via Src-EGFR-ERK1/2-CREB pathway in rat Sertoli cells†","year":2017,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sertoli cell; Ouabain; Claudin; Connexin; Cell biology; Biology; Signal transduction; Proto-oncogene tyrosine-protein kinase Src; Internal medicine; Gene isoform; Endocrinology; Gap junction; Tight junction; Chemistry; Intracellular; Biochemistry; Sodium; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008069241,0.0001996828,0.0003033526,0.00007043681,0.0002932377,0.00001487438,0.0002715259,0.0003610978,0.00001310328],"category_scores_gemma":[0.0004205054,0.0001480326,0.00009271365,0.00005259247,0.0009686,0.00001221547,0.0002047424,0.0001350403,0.000002384236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001808465,"about_ca_system_score_gemma":0.00008865929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000454881,"about_ca_topic_score_gemma":0.0007501143,"domain_scores_codex":[0.9983611,0.0001539867,0.0004452738,0.000691654,0.00006809909,0.0002799621],"domain_scores_gemma":[0.9982241,0.00003694283,0.0004927101,0.001015096,0.0001859781,0.00004521928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000515687,0.00007781696,0.007772152,0.00003634445,0.0000458617,0.000001783492,0.00004271628,0.000005969584,0.9509603,0.0007500657,0.0002743007,0.03951705],"study_design_scores_gemma":[0.0006900784,0.000718024,0.01057607,0.00001782537,0.00001054477,0.00007082402,0.0001034056,0.00002564281,0.9069786,0.0008253373,0.07981524,0.0001683768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927881,0.004328842,0.0001180235,0.001354765,0.0008308996,0.0004244865,0.00002285031,0.00001066969,0.0001213661],"genre_scores_gemma":[0.9974208,0.0009812146,0.0002826249,0.00002566245,0.000414999,0.00003879449,0.00008681753,0.00001558069,0.0007334927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07954094,"threshold_uncertainty_score":0.6036595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01036735693037872,"score_gpt":0.2383275261463746,"score_spread":0.2279601692159959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}