{"id":"W2588707314","doi":"10.1182/blood.v126.23.3467.3467","title":"Safety and Efficacy of Long-Term Open-Label Dosing of Subcutaneous (SC) Romiplostim in Pediatric Patients with Immune Thrombocytopenia (ITP)","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Romiplostim; Medicine; Dosing; Adverse effect; Splenectomy; Placebo; Internal medicine; Clinical endpoint; Incidence (geometry); Pediatrics; Surgery; Thrombopoietin; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001226771,0.0004157793,0.0008166732,0.000140571,0.0001983443,0.0004521648,0.000323245,0.0004894569,0.0014791],"category_scores_gemma":[0.00143811,0.000140068,0.0005293397,0.0002256047,0.0003097949,0.0005524328,0.000208508,0.001583141,0.0003647144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004201587,"about_ca_system_score_gemma":0.0004903149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000292101,"about_ca_topic_score_gemma":0.0004095074,"domain_scores_codex":[0.9996018,0.0002029645,0.00003278585,0.00005930684,0.00005296393,0.00005034209],"domain_scores_gemma":[0.9987668,0.0002786541,0.000520726,0.00009946792,0.00008156198,0.0002527466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5161865,0.02530554,0.05432786,0.001191806,0.001103989,0.0004849495,0.0003998187,0.002008283,0.02439122,0.0002481687,0.003686039,0.3706658],"study_design_scores_gemma":[0.117356,0.7337425,0.1289631,0.0001958834,0.0006923166,0.001295751,0.000174968,0.002650992,0.008541195,0.0001475417,0.006205413,0.00003414699],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954247,0.002760682,0.0003062894,0.0001014993,0.00002962505,0.000232149,0.0004025227,0.00003996186,0.0007025765],"genre_scores_gemma":[0.9976567,0.0006403088,0.0003828015,0.0001413975,0.00005242041,0.0002857439,0.0005319112,0.000005058368,0.0003035847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0014791,"threshold_uncertainty_score":0.006487846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02050000216742284,"score_gpt":0.2692801031106963,"score_spread":0.2487801009432735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}