{"id":"W2588715080","doi":"10.1038/bjc.2017.38","title":"Oncogenic role of PDK4 in human colon cancer cells","year":2017,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"PDK4; Cancer research; Downregulation and upregulation; Apoptosis; Biology; Colorectal cancer; DNA methylation; Cancer; Methylation; Gene; Gene expression; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001452569,0.0002052757,0.0001820252,0.0003540527,0.0002375549,0.0002630118,0.000115921,0.0002174049,0.001488132],"category_scores_gemma":[0.0002091597,0.0001150591,0.0001612482,0.0003826651,0.0001924666,0.00009335428,0.0002034229,0.0003463343,0.0003636225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005390255,"about_ca_system_score_gemma":0.0003485875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001755464,"about_ca_topic_score_gemma":0.001365326,"domain_scores_codex":[0.999864,0.00002305943,0.00001103218,0.00003036145,0.00004865387,0.00002281795],"domain_scores_gemma":[0.9999317,0.00001512862,0.0000128913,0.00001279163,0.0000164296,0.00001110737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000611098,0.00004852016,0.002485425,0.0001545038,0.00001850685,0.0001582367,0.0000424266,0.0002897585,0.9893509,0.0001554743,0.0002342493,0.006450912],"study_design_scores_gemma":[0.00005892101,0.0007951217,0.02502156,0.00001565099,0.00004974553,0.001546058,0.00008323097,0.002404454,0.957739,0.0001882515,0.01208864,0.000009410986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895912,0.003826871,0.002474597,0.0001525369,0.00002931598,0.00004727659,0.001440681,0.000114211,0.002323325],"genre_scores_gemma":[0.9937229,0.001136688,0.001911171,0.00004649106,0.000003038475,0.00004730748,0.001352644,0.00001065988,0.001769065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001755464,"threshold_uncertainty_score":0.00497824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01064761126201411,"score_gpt":0.3322914874620145,"score_spread":0.3216438762000003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}