{"id":"W2588715080","doi":"10.1038/bjc.2017.38","title":"Oncogenic role of PDK4 in human colon cancer cells","year":2017,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"PDK4; Cancer research; Downregulation and upregulation; Apoptosis; Biology; Colorectal cancer; DNA methylation; Cancer; Methylation; Gene; Gene expression; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001993077,0.00007611662,0.0002200255,0.00002826723,0.0001005996,0.00003413979,0.0003949185,0.00009703597,0.00008055138],"category_scores_gemma":[0.00009389287,0.00007989226,0.0001120146,0.00002862986,0.000219266,0.000007373241,0.0001608722,0.0001925851,6.082855e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004327271,"about_ca_system_score_gemma":0.0001531537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002196711,"about_ca_topic_score_gemma":0.003758696,"domain_scores_codex":[0.9991503,0.00003055521,0.0002873361,0.0001279679,0.0002048187,0.0001990441],"domain_scores_gemma":[0.9991606,0.000005850947,0.0003445701,0.0001520132,0.0002645366,0.00007235764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001089076,0.00005847923,0.007422822,0.00002290694,0.0001034428,0.00002785215,0.00001448893,0.000015727,0.9681731,0.000001832949,0.003696201,0.02035422],"study_design_scores_gemma":[0.0008205954,0.0001903404,0.02860133,0.0002116111,0.00001768994,0.00002694248,0.00002999108,0.000002064168,0.9512928,0.00007907084,0.01863845,0.00008915403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9543525,0.04455656,0.000002390393,0.0001702518,0.0001220886,0.0000662218,0.00005653813,7.368362e-7,0.0006727232],"genre_scores_gemma":[0.9790419,0.02010496,0.00006191436,0.0000457163,0.0003671289,0.00001181573,0.000001730643,0.00001072941,0.0003541527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02468937,"threshold_uncertainty_score":0.3320784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01064761126201411,"score_gpt":0.3322914874620145,"score_spread":0.3216438762000003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}