{"id":"W2588715533","doi":"10.1101/094144","title":"A systematic cell size screen uncovers coupling of growth to division by the p38/HOG network in <i>Candida albicans</i>","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Université Laval; Université de Montréal; University of British Columbia; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Centre Hospitalier Universitaire de Québec; Génome Québec; Wellcome Trust; National Institutes of Health; Fondation CHU de Québec; Université Laval","keywords":"Ribosome biogenesis; Candida albicans; Biology; Cell biology; Transcription factor; Regulator; Transcriptional regulation; Genetics; Biogenesis; Regulon; Cell division; Cell cycle; Promoter; Gene; Cell; Ribosome; Gene expression; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000153189,0.0003405678,0.0002212602,0.0004825116,0.0002645878,0.0003659089,0.0004482417,0.0002339774,0.001229823],"category_scores_gemma":[0.0001916238,0.0002131943,0.0002832699,0.0003543445,0.0002597287,0.0001170061,0.000357842,0.000466841,0.000310111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000543254,"about_ca_system_score_gemma":0.0003559618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002771143,"about_ca_topic_score_gemma":0.005134545,"domain_scores_codex":[0.9998426,0.00001029416,0.00001061385,0.0000473845,0.00005158797,0.00003748637],"domain_scores_gemma":[0.9998279,0.00003729569,0.00004414811,0.00002543655,0.00002264498,0.00004261755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007530188,0.00001673794,0.0006401382,0.00001355829,0.000004538565,0.00003909909,0.000005083334,0.00009118777,0.9976745,0.00006720104,0.00007930218,0.001293404],"study_design_scores_gemma":[0.00002717122,0.0002299251,0.04519831,0.000006552587,0.00003348374,0.0002888283,0.00004371965,0.003734982,0.9477451,0.0001466086,0.002525967,0.0000194357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913957,0.0002575882,0.003199603,0.00009347343,0.00001514372,0.00004463514,0.003058563,0.0003569345,0.00157848],"genre_scores_gemma":[0.9921252,0.0001890463,0.003610009,0.0001208855,0.000005149343,0.0000524253,0.002219161,0.00009629651,0.001581769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002771143,"threshold_uncertainty_score":0.005510032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005863217098926956,"score_gpt":0.2120604368500191,"score_spread":0.2061972197510921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}