{"id":"W2588865017","doi":"10.1161/circgenetics.116.001598","title":"Hyaluronidase 2 Deficiency Causes Increased Mesenchymal Cells, Congenital Heart Defects, and Heart Failure","year":2017,"lang":"en","type":"article","venue":"Circulation Cardiovascular Genetics","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital Research Institute of Manitoba","funders":"University of Manitoba","keywords":"Mesenchymal stem cell; Heart failure; Internal medicine; Cardiac fibrosis; Endocrinology; Biology; Fibrosis; Medicine; Cancer research; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002445653,0.001200693,0.0003225333,0.00104169,0.0002245919,0.0002569437,0.0002513734,0.0006313851,0.001813321],"category_scores_gemma":[0.0002613208,0.0002994273,0.0003260995,0.0003373522,0.0006366725,0.0002154242,0.0004443312,0.0007071496,0.000254583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002601306,"about_ca_system_score_gemma":0.0002551487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004429296,"about_ca_topic_score_gemma":0.0007079347,"domain_scores_codex":[0.9997188,0.00003499196,0.00004527187,0.00007968977,0.00008850886,0.00003263041],"domain_scores_gemma":[0.9994563,0.000086183,0.000220341,0.00002608443,0.00001934303,0.0001918355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003485594,0.00008072338,0.004302166,0.00009550314,0.00003956527,0.002544522,0.00003863639,0.0001547501,0.9896476,0.0001473111,0.0001242452,0.002476482],"study_design_scores_gemma":[0.0002695043,0.002123777,0.2414614,0.00007572927,0.0002597395,0.04962557,0.0001859728,0.001406559,0.6993856,0.0003385941,0.004814582,0.0000530521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953105,0.001332072,0.001557714,0.0000859951,0.00002825971,0.00004240886,0.0008339439,0.0001054824,0.000703712],"genre_scores_gemma":[0.9942076,0.001210892,0.002142257,0.0001003062,0.00003030964,0.00007732195,0.0008479126,0.00004015467,0.001343243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001813321,"threshold_uncertainty_score":0.006066144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01512022078174154,"score_gpt":0.2530394994786297,"score_spread":0.2379192786968882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}