{"id":"W2588865522","doi":"10.1182/blood.v118.21.634.634","title":"Randomized, Open Label Phase 1/2 Study of Pomalidomide (POM) Alone or in Combination with Low-Dose Dexamethasone (LoDex) in Patients (Pts) with Relapsed and Refractory Multiple Myeloma Who Have Received Prior Treatment That Includes Lenalidomide (LEN) and Bortezomib (BORT): Phase 2 Results","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Pomalidomide; Neutropenia; Internal medicine; Clinical endpoint; Population; Phases of clinical research; Lenalidomide; Adverse effect; Dexamethasone; Febrile neutropenia; Regimen; Surgery; Gastroenterology; Randomized controlled trial; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003384364,0.003126058,0.003862479,0.0006717706,0.0007563726,0.002018514,0.001446182,0.00263555,0.01070591],"category_scores_gemma":[0.003218601,0.001600415,0.002068112,0.0006733435,0.002173789,0.002181273,0.0007542752,0.005021793,0.001882094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00132643,"about_ca_system_score_gemma":0.002304889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000846982,"about_ca_topic_score_gemma":0.002263932,"domain_scores_codex":[0.9987148,0.0007625779,0.00006368621,0.0002209099,0.00007805551,0.0001598808],"domain_scores_gemma":[0.9978809,0.0005726916,0.0004539634,0.0002198573,0.0001391164,0.0007335739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9705434,0.01946913,0.0004974551,0.0001885744,0.0004238978,0.00003583658,0.00004625231,0.0002551682,0.002308905,0.00007755236,0.0006717316,0.005482121],"study_design_scores_gemma":[0.9294406,0.06889325,0.0005626727,0.000008308626,0.0001603919,0.00002212998,0.00001215599,0.0002308703,0.0001907384,0.0001016727,0.0003674793,0.000009614838],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740296,0.002034846,0.001353526,0.001154444,0.0007558787,0.01474443,0.002862755,0.0002343933,0.002830033],"genre_scores_gemma":[0.964982,0.002041176,0.004686591,0.002137875,0.0008866482,0.01714759,0.002824242,0.00009545165,0.005198364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01070591,"threshold_uncertainty_score":0.03581488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06689704075909599,"score_gpt":0.3376607847148975,"score_spread":0.2707637439558015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}