{"id":"W2588955044","doi":"10.1186/s12915-017-0349-7","title":"Enhancing circadian clock function in cancer cells inhibits tumor growth","year":2017,"lang":"en","type":"article","venue":"BMC Biology","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont; McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Biology; Circadian rhythm; Circadian clock; Function (biology); Cancer; Cell biology; Cancer research; Cancer cell; Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337312,0.0002575775,0.0002958276,0.0001348291,0.0001365043,0.0002339769,0.000205114,0.0001787227,0.001210221],"category_scores_gemma":[0.0001186664,0.00006570361,0.0001661547,0.0001793871,0.0001958268,0.0001148956,0.0001555522,0.0005508473,0.000307325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000313557,"about_ca_system_score_gemma":0.0003937581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006482951,"about_ca_topic_score_gemma":0.001540534,"domain_scores_codex":[0.9998931,0.00001532877,0.00001134774,0.00002359291,0.00002550463,0.00003115911],"domain_scores_gemma":[0.9998924,0.00001638724,0.00003123567,0.00001757641,0.00000930639,0.00003318227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002561221,0.0000795224,0.0002658138,0.00008457047,0.000007101814,0.00002120139,0.00001250355,0.0001247448,0.9944531,0.0001258815,0.0001502546,0.004419184],"study_design_scores_gemma":[0.00004403841,0.0009159739,0.00278701,0.000009078399,0.00001862372,0.0001043836,0.00002276355,0.0008172399,0.9896803,0.0000442268,0.005552476,0.000003830909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866333,0.006575371,0.003560421,0.0002285344,0.0001993029,0.00005086022,0.0004146096,0.0003042805,0.002033191],"genre_scores_gemma":[0.9935221,0.002342653,0.001942254,0.0000613314,0.00001878962,0.00003976243,0.000319471,0.00002420469,0.001729444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001210221,"threshold_uncertainty_score":0.004048586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0400708683430772,"score_gpt":0.2880244664889762,"score_spread":0.247953598145899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}