{"id":"W2589032563","doi":"10.1016/j.lfs.2017.02.005","title":"Rolipram potentiates bevacizumab-induced cell death in human glioblastoma stem-like cells","year":2017,"lang":"en","type":"article","venue":"Life Sciences","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Iran National Science Foundation; Iran University of Medical Sciences","keywords":"Vascular endothelial growth factor A; Rolipram; Protein kinase B; Cancer research; Angiogenesis; Apoptosis; Chemistry; Vascular endothelial growth factor; Biology; Biochemistry; Phosphodiesterase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001356925,0.0002508477,0.0004745852,0.0002632411,0.0001301816,0.000255842,0.0002306173,0.0002400715,0.00118112],"category_scores_gemma":[0.000149339,0.000105868,0.0003149561,0.0001924713,0.0001228157,0.0001438631,0.0001479249,0.0006227888,0.0003736369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002065004,"about_ca_system_score_gemma":0.0002586098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001519911,"about_ca_topic_score_gemma":0.002951378,"domain_scores_codex":[0.9998889,0.00002574525,0.00001176677,0.00001141068,0.00002112564,0.00004098063],"domain_scores_gemma":[0.9999427,0.00001442277,0.00001183345,0.000007720043,0.000007583673,0.00001575039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002561163,0.000625118,0.0009658058,0.0001373402,0.00006177656,0.0003850673,0.0001018047,0.0003726705,0.977431,0.0002423552,0.0006642666,0.01645171],"study_design_scores_gemma":[0.0005479134,0.005172727,0.01360038,0.00001995913,0.0001477706,0.0006447925,0.0001210283,0.002154505,0.9717854,0.0001013005,0.005689563,0.00001451937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961582,0.001550274,0.0003909608,0.0001257872,0.000046667,0.00002851233,0.0003009973,0.00006556162,0.001333142],"genre_scores_gemma":[0.9971974,0.0007398151,0.0003788366,0.0000590207,0.0000118724,0.00003162584,0.0004874398,0.000006747743,0.001087238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519911,"threshold_uncertainty_score":0.003951252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02255754366575624,"score_gpt":0.277380133585571,"score_spread":0.2548225899198148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}