{"id":"W2589058173","doi":"10.1093/neuonc/now212.155","title":"CBIO-17. STAT3 IS A CENTRAL REGULATOR OF PROLIFERATION, INVASION, MIGRATION AND METABOLISM IN GBM TUMOR INITIATING CELLS","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Brain Institute; University of Calgary","funders":"","keywords":"STAT3; STAT protein; Cancer research; Biology; Regulator; Signal transduction; Cell growth; Gene signature; Activator (genetics); Gene expression; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000175145,0.0003783328,0.0003391917,0.0004952651,0.0003582334,0.0004444334,0.0003123641,0.0002523002,0.005229104],"category_scores_gemma":[0.00007598218,0.0001856845,0.0004348263,0.0005561564,0.0003017592,0.0001502785,0.0002253708,0.0008110185,0.002139361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007845762,"about_ca_system_score_gemma":0.0008278645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002442678,"about_ca_topic_score_gemma":0.004299382,"domain_scores_codex":[0.9998294,0.00001124938,0.00001288353,0.00002931086,0.00007078426,0.00004636287],"domain_scores_gemma":[0.9999243,0.000006090479,0.00001870913,0.000007765387,0.0000118824,0.00003123511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005606919,0.0001112395,0.001204192,0.0002686968,0.00001810911,0.0001717153,0.0000223752,0.000200352,0.9852297,0.0004594736,0.00188105,0.009872499],"study_design_scores_gemma":[0.0001648222,0.000669746,0.02391381,0.00006267005,0.00006166961,0.001092188,0.00005982494,0.001143741,0.9146502,0.0003445627,0.05781907,0.00001762631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8970813,0.0383238,0.009257142,0.002113363,0.0007843364,0.0003414915,0.02512947,0.001315929,0.02565326],"genre_scores_gemma":[0.925329,0.01401824,0.006153324,0.0008886948,0.00008633506,0.0004090053,0.02690122,0.0001672777,0.02604689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005229104,"threshold_uncertainty_score":0.01749313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0207012419564813,"score_gpt":0.2767365507703716,"score_spread":0.2560353088138902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}