{"id":"W2589347345","doi":"10.1182/blood.v112.11.892.892","title":"The SH2-B Adaptor Protein Negatively Regulates EPO-Dependent Signalling Via Interaction with Erythropoietin Receptor Ptyr-343","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Erythropoietin; Erythropoietin receptor; Signal transducing adaptor protein; Erythropoiesis; SH2 domain; Cell biology; STAT5; Biology; Haematopoiesis; Signal transduction; Janus kinase 2; Chemistry; Tyrosine phosphorylation; Internal medicine; Endocrinology; Stem cell; Anemia; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002005307,0.0002418529,0.000271905,0.00008595938,0.0006019089,0.00005268838,0.0001192459,0.00008449721,0.0003385099],"category_scores_gemma":[0.0001317418,0.0001528422,0.0001315015,0.0002069251,0.0001653663,0.0001841402,0.0000385857,0.000474193,0.000115602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008396141,"about_ca_system_score_gemma":0.0001456829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001925256,"about_ca_topic_score_gemma":0.00004959426,"domain_scores_codex":[0.9984152,0.00008196465,0.0003967969,0.0003635582,0.0004209694,0.0003215229],"domain_scores_gemma":[0.998867,0.0001564859,0.0002396249,0.0003156739,0.0002819205,0.0001392642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008159715,0.0007835916,0.00062444,0.00003338144,0.0003240436,0.00008109079,0.0007525198,0.00004683258,0.9939111,0.0001022781,0.001070539,0.001454244],"study_design_scores_gemma":[0.002400297,0.001511557,0.0009995757,0.0005125787,0.0001666708,0.0007753287,0.0007725483,0.0003147297,0.9809226,0.00004681479,0.01132726,0.0002500089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940574,0.0002591219,0.001315264,0.001678301,0.0002089662,0.0008042598,0.00001212353,0.0001621123,0.001502432],"genre_scores_gemma":[0.9940442,0.00006978323,0.002549309,0.00008848935,0.0005647942,0.0001326158,0.00002329006,0.0000535876,0.002473886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01298844,"threshold_uncertainty_score":0.6232725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02149927829153884,"score_gpt":0.2402855583950254,"score_spread":0.2187862801034866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}