{"id":"W2589428111","doi":"10.1200/jco.2005.23.16_suppl.5566","title":"A phase II study of BAY 43–9006 in patients with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) and nasopharyngeal cancer (NPC)","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bayer (Canada)","funders":"","keywords":"Medicine; Head and neck squamous-cell carcinoma; Internal medicine; Oncology; Progressive disease; Cancer; KRAS; Head and neck cancer; Chemotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006551585,0.0001452809,0.0007494103,0.0000680229,0.00003610173,0.000005637277,0.00009045064,0.0001381793,0.00001348738],"category_scores_gemma":[0.0002166711,0.00009516155,0.00005612388,0.00005354207,0.0001201318,0.00001178772,0.0001051811,0.0002804083,1.660591e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002099412,"about_ca_system_score_gemma":0.0003476191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005056077,"about_ca_topic_score_gemma":0.001509516,"domain_scores_codex":[0.9980747,0.0002837665,0.00107359,0.0002406266,0.0001516697,0.0001757254],"domain_scores_gemma":[0.9986043,0.0001735095,0.000739102,0.0001170349,0.0001492394,0.0002167889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0198144,0.02038835,0.826134,0.00008715585,0.0001561518,0.0001118426,0.0006429134,0.00001406735,0.001642615,0.000004413545,0.0004908031,0.1305133],"study_design_scores_gemma":[0.07044181,0.2550132,0.666199,0.00003534443,0.0002943342,0.00004488723,0.0002541544,0.00006766581,0.0006137656,0.00001016377,0.006843199,0.0001825557],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974009,0.001851254,0.00000586886,0.0001738031,0.0001745002,0.0002902294,0.00001722668,9.548207e-7,0.00008531178],"genre_scores_gemma":[0.998506,0.0003113369,0.0006920586,0.0002173361,0.0002086319,0.000007494704,0.000004244911,0.00001104953,0.00004186674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2346248,"threshold_uncertainty_score":0.3880575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05488710328573179,"score_gpt":0.3927872439765381,"score_spread":0.3379001406908063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}