{"id":"W2589428111","doi":"10.1200/jco.2005.23.16_suppl.5566","title":"A phase II study of BAY 43–9006 in patients with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) and nasopharyngeal cancer (NPC)","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bayer (Canada)","funders":"","keywords":"Medicine; Head and neck squamous-cell carcinoma; Internal medicine; Oncology; Progressive disease; Cancer; KRAS; Head and neck cancer; Chemotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001148735,0.001139182,0.001913121,0.0003699255,0.0003920758,0.0006449386,0.0006996272,0.0009036624,0.003171534],"category_scores_gemma":[0.0005332957,0.0006118856,0.0009644988,0.0004643745,0.000851076,0.00064887,0.0003969403,0.002400652,0.000976569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006322882,"about_ca_system_score_gemma":0.001469253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001605201,"about_ca_topic_score_gemma":0.003098309,"domain_scores_codex":[0.9997007,0.000119688,0.00001838431,0.00005938697,0.00002942954,0.00007255137],"domain_scores_gemma":[0.9995796,0.0000462071,0.00006144209,0.00003811074,0.00002554747,0.0002490641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6244953,0.1306731,0.02160975,0.0009814579,0.001396201,0.0005685049,0.0006716177,0.003683137,0.08278412,0.000385482,0.004302344,0.128449],"study_design_scores_gemma":[0.4268242,0.5444684,0.0209481,0.00002306598,0.0003930972,0.0004500903,0.00009326892,0.001182389,0.002991743,0.0001145172,0.00248638,0.00002480062],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954569,0.001110782,0.0003250194,0.0001735811,0.00007789591,0.001632634,0.0003451297,0.00005070621,0.0008273785],"genre_scores_gemma":[0.9917758,0.001512149,0.001160302,0.0005257236,0.0001143403,0.001634521,0.001387088,0.00001577238,0.001874441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003171534,"threshold_uncertainty_score":0.01060987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05488710328573179,"score_gpt":0.3927872439765381,"score_spread":0.3379001406908063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}