{"id":"W2590133597","doi":"10.1182/blood.v114.22.1866.1866","title":"Prolonged Use of Lenalidomide (≥12 Cycles) for Multiple Myeloma (MM) Is Frequently Affected by Dose-Limiting Thrombocytopenia but Is Associated with Improved Quality of Response and Survival.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Lenalidomide; Medicine; Multiple myeloma; Dexamethasone; Internal medicine; Data monitoring committee; Refractory (planetary science); Surgery; Oncology; Randomized controlled trial; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005352714,0.0002215735,0.0005544747,0.0002368363,0.0003738172,0.0004321466,0.0003006786,0.0002659789,0.00480636],"category_scores_gemma":[0.0008311424,0.0001169437,0.0003318647,0.0005792698,0.0002161449,0.0002937932,0.0004368142,0.0006736687,0.000711687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008707785,"about_ca_system_score_gemma":0.0005884063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006413421,"about_ca_topic_score_gemma":0.002084682,"domain_scores_codex":[0.9996604,0.00008154671,0.00004585586,0.00007808441,0.0000823681,0.00005173222],"domain_scores_gemma":[0.9992404,0.000131413,0.0003518936,0.00005203158,0.00005361933,0.0001706606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01354722,0.003036878,0.4901953,0.0006925586,0.0004337078,0.000918922,0.0002343234,0.0007711255,0.04935446,0.0001701551,0.005718848,0.4349264],"study_design_scores_gemma":[0.001286699,0.02746364,0.9373397,0.0001240424,0.0002434199,0.003823027,0.0001156577,0.000528381,0.01157462,0.0001864577,0.0172843,0.00003013362],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896283,0.004239455,0.000738758,0.0003220025,0.00003363831,0.0002926927,0.0008529985,0.00005542381,0.003836751],"genre_scores_gemma":[0.9947935,0.001234192,0.0008292372,0.0003823193,0.00007799589,0.0001704653,0.001102946,0.00001564211,0.001393599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00480636,"threshold_uncertainty_score":0.01607889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06479940935999418,"score_gpt":0.3268451912349983,"score_spread":0.2620457818750042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}