{"id":"W2590406373","doi":"10.1093/ecco-jcc/jjx005","title":"Eldelumab [anti-interferon-γ-inducible protein-10 antibody] Induction Therapy for Active Crohn’s Disease: a Randomised, Double-blind, Placebo-controlled Phase IIa Study","year":2017,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Bristol-Myers Squibb","keywords":"Medicine; Crohn's disease; Placebo; Double blind; Antibody; Internal medicine; Gastroenterology; Disease; Induction therapy; Immunology; Pathology; Alternative medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007045605,0.0002918986,0.000572363,0.0001153847,0.0005916849,0.0003661018,0.0003560972,0.000144386,0.00007366183],"category_scores_gemma":[0.0002159544,0.0002365588,0.0003967602,0.0000273225,0.0001386244,0.00007334082,0.00008339838,0.0001744373,0.000001970288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003528944,"about_ca_system_score_gemma":0.0004360289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000170042,"about_ca_topic_score_gemma":0.00001918368,"domain_scores_codex":[0.9982519,0.0001501973,0.0006232157,0.0003674898,0.0002704897,0.0003367552],"domain_scores_gemma":[0.9975237,0.00002261233,0.0009981683,0.0005178634,0.0006065763,0.0003311127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9772655,0.001115383,0.0003080058,0.0000410806,0.0008329958,0.0004289197,0.0001466192,0.000006952884,0.01403642,0.00002700444,0.0006191349,0.005171949],"study_design_scores_gemma":[0.7539895,0.003187533,0.2188422,0.0001204756,0.0004439034,0.00006058283,0.0004906197,0.00005212543,0.01868462,0.0001410222,0.003530578,0.0004568954],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938926,0.0004475383,0.0003240711,0.0002182356,0.0003449529,0.004453266,0.0000695347,0.000006698987,0.0002430771],"genre_scores_gemma":[0.9972114,0.0002080163,0.00004854939,0.00004751281,0.0009395775,0.000483075,0.00002408339,0.00003869437,0.0009991102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2232761,"threshold_uncertainty_score":0.9646587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02345367364003952,"score_gpt":0.3310734457759404,"score_spread":0.3076197721359009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}