{"id":"W2590406373","doi":"10.1093/ecco-jcc/jjx005","title":"Eldelumab [anti-interferon-γ-inducible protein-10 antibody] Induction Therapy for Active Crohn’s Disease: a Randomised, Double-blind, Placebo-controlled Phase IIa Study","year":2017,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Bristol-Myers Squibb","keywords":"Medicine; Crohn's disease; Placebo; Double blind; Antibody; Internal medicine; Gastroenterology; Disease; Induction therapy; Immunology; Pathology; Alternative medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004856198,0.001301596,0.003228181,0.000454264,0.0004665912,0.0009542684,0.0009965897,0.002156692,0.005447769],"category_scores_gemma":[0.001868137,0.0008043733,0.001657305,0.0004660524,0.001270693,0.0008183784,0.0003885571,0.002550152,0.001197799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005944318,"about_ca_system_score_gemma":0.001376354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000390527,"about_ca_topic_score_gemma":0.001002335,"domain_scores_codex":[0.9987858,0.0007353919,0.0001018815,0.0001404266,0.0001102062,0.0001262393],"domain_scores_gemma":[0.9986236,0.0004099914,0.0003513764,0.0001233401,0.0001085462,0.0003830463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9611112,0.01350076,0.0008505188,0.001113574,0.0006089783,0.00006772741,0.00006513345,0.0002253262,0.006585234,0.00007221836,0.0005861278,0.01521314],"study_design_scores_gemma":[0.9306037,0.06665576,0.001621733,0.00003103324,0.0001889469,0.00003513952,0.000007707498,0.00008844654,0.0002725936,0.00002828423,0.0004584032,0.000008257025],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726114,0.008362624,0.001564404,0.0008777618,0.0007009814,0.01206539,0.001277628,0.0001314811,0.002408243],"genre_scores_gemma":[0.9689028,0.007572595,0.003258578,0.002125101,0.001168443,0.01035621,0.00184652,0.00003062723,0.004739146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005447769,"threshold_uncertainty_score":0.02568233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02345367364003952,"score_gpt":0.3310734457759404,"score_spread":0.3076197721359009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}