{"id":"W2590926364","doi":"10.1200/jco.2008.26.15_suppl.5045","title":"Safety and efficacy of sorafenib in elderly patients (pts) ≥65 years: A subset analysis from the Advanced Renal Cell Carcinoma Sorafenib (ARCCS) Expanded Access Program in North America","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Sorafenib; Expanded access; Internal medicine; Renal cell carcinoma; Adverse effect; Oncology; Clinical trial; Hepatocellular carcinoma","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005667558,0.0002487172,0.0004403743,0.0004050834,0.0003025543,0.0004292774,0.0001761262,0.000215641,0.001113571],"category_scores_gemma":[0.0006982347,0.0001708945,0.0007646796,0.0005888506,0.0001596059,0.0002109772,0.000359949,0.0003356673,0.0001954791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003826099,"about_ca_system_score_gemma":0.000472667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003041326,"about_ca_topic_score_gemma":0.004705962,"domain_scores_codex":[0.9996481,0.00009407128,0.00003722637,0.00008676721,0.00007978488,0.00005406703],"domain_scores_gemma":[0.9992648,0.0001130041,0.0002464031,0.00005568995,0.00009657258,0.0002234528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007332435,0.000462847,0.9795274,0.0000519406,0.0005936571,0.0004852562,0.000205764,0.0002479118,0.002448291,0.00002942769,0.0009491699,0.007665854],"study_design_scores_gemma":[0.0005480964,0.00182773,0.9949979,0.000008377932,0.0002890561,0.000685052,0.0001686646,0.0004272241,0.0002272881,0.00002084451,0.0007920163,0.000007799968],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990752,0.0001157291,0.00004828138,0.00002120004,0.000003071864,0.00002832964,0.0004855797,0.00000234663,0.0002203683],"genre_scores_gemma":[0.9983934,0.00007971857,0.00005641179,0.00006403581,0.00001480036,0.00002903567,0.001221094,0.00000254874,0.0001390424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003041326,"threshold_uncertainty_score":0.006047249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07165830181736565,"score_gpt":0.3975656160024058,"score_spread":0.3259073141850401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}