{"id":"W2590948392","doi":"10.1128/aac.01997-16","title":"Exopolysaccharide-Repressing Small Molecules with Antibiofilm and Antivirulence Activity against Pseudomonas aeruginosa","year":2017,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Athabasca University; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Pseudomonas aeruginosa; Microbiology; Biofilm; Chemistry; Pseudomonadaceae; Pseudomonadales; Biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009783979,0.0004767378,0.0004105089,0.0003787137,0.0001458802,0.0002476651,0.0001836208,0.000218353,0.001293911],"category_scores_gemma":[0.0001040383,0.0001232747,0.000322089,0.0002529407,0.000120533,0.000138867,0.0001501303,0.0004318449,0.0002251371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001680296,"about_ca_system_score_gemma":0.000146148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004689267,"about_ca_topic_score_gemma":0.00104905,"domain_scores_codex":[0.9999238,0.00001234403,0.000006438182,0.0000122604,0.00003031142,0.00001479432],"domain_scores_gemma":[0.9999291,0.00001822583,0.00001482698,0.000005342175,0.00001749942,0.00001501735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007249605,0.00008391983,0.00009036608,0.00009095132,0.000007453268,0.0000352613,0.000003937663,0.0001536219,0.997169,0.00002368583,0.00006556703,0.00220375],"study_design_scores_gemma":[0.00007801969,0.002168294,0.003960623,0.00002156091,0.00005878938,0.0002447337,0.0000243061,0.001140138,0.9889976,0.0000340424,0.003260436,0.00001130047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841444,0.007730281,0.003850061,0.0002319831,0.00006525735,0.0001514099,0.001553193,0.0001610548,0.002112353],"genre_scores_gemma":[0.9814441,0.006077609,0.006201414,0.0001924501,0.00003446572,0.0001446816,0.002272555,0.00002775898,0.003604962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001293911,"threshold_uncertainty_score":0.004328489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01358538563332047,"score_gpt":0.2398824271557566,"score_spread":0.2262970415224361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}