{"id":"W2591178945","doi":"10.1093/carcin/bgx020","title":"17β-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells","year":2017,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Eicosapentaenoic acid; Biology; Arachidonic acid; Estrogen receptor; Endocrinology; Protein kinase B; Estrogen; Internal medicine; Cancer research; Polyunsaturated fatty acid; Fatty acid; Signal transduction; Cell biology; Biochemistry; Cancer; Breast cancer; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001113617,0.0002198211,0.0002019004,0.000287073,0.0001763571,0.0002401721,0.0001039282,0.0001723119,0.002358435],"category_scores_gemma":[0.00007525423,0.0001622535,0.0003507765,0.0002547049,0.0001621724,0.0001241517,0.0001747328,0.0004694797,0.0008839382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003094058,"about_ca_system_score_gemma":0.0002508307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001242016,"about_ca_topic_score_gemma":0.001202338,"domain_scores_codex":[0.9998664,0.00001450828,0.00001280909,0.00002275539,0.0000476895,0.00003590262],"domain_scores_gemma":[0.9999166,0.00001302349,0.00001902914,0.00001103575,0.00002034171,0.00001991462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000062688,0.00001637952,0.0002297311,0.00002311315,0.000003853742,0.000040183,0.00001939912,0.00001499538,0.998962,0.00003751788,0.00004711828,0.0005429866],"study_design_scores_gemma":[0.00001303084,0.0001561104,0.00972993,0.000004997993,0.0000149282,0.0002642518,0.0000771506,0.0004837278,0.984324,0.00003696128,0.004890041,0.000004911167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917184,0.001710615,0.002163551,0.0002328879,0.00006383064,0.00002892419,0.00116974,0.0001130355,0.002799042],"genre_scores_gemma":[0.9722617,0.002156513,0.002920632,0.0001613928,0.00002302359,0.0001028116,0.003213602,0.00004467805,0.01911556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002358435,"threshold_uncertainty_score":0.007889748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01775111187737062,"score_gpt":0.2477921375141309,"score_spread":0.2300410256367603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}