{"id":"W2591295589","doi":"10.3390/pharmaceutics9010009","title":"Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target","year":2017,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Lung; Hydroxyeicosatetraenoic acid; Kidney; Medicine; Internal medicine; Chemistry; Biochemistry; Arachidonic acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004770142,0.0004192471,0.001084634,0.0005366051,0.0002169067,0.0008049496,0.000373752,0.0009631867,0.0031144],"category_scores_gemma":[0.0005000127,0.00007637329,0.0004089235,0.0004576526,0.0003587645,0.0006829847,0.0004037328,0.001708046,0.0008860113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003884509,"about_ca_system_score_gemma":0.0008458356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004100366,"about_ca_topic_score_gemma":0.0008420749,"domain_scores_codex":[0.9998412,0.00004576645,0.00002208251,0.00002588467,0.00004272914,0.00002239674],"domain_scores_gemma":[0.999774,0.00006815635,0.00003765053,0.000008265023,0.00007203916,0.00003989536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001592117,0.0003870954,0.002185754,0.01137492,0.0002913811,0.002514416,0.0001110454,0.0003825841,0.02081284,0.007912063,0.03428518,0.9181507],"study_design_scores_gemma":[0.0006856626,0.002276468,0.009263069,0.005340598,0.001022936,0.01530384,0.0003511676,0.000978724,0.01319037,0.01836392,0.9331356,0.00008769541],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002317159,0.9902222,0.0006798836,0.003961793,0.0005944084,0.00001084696,0.00005455898,0.00002187038,0.002137277],"genre_scores_gemma":[0.03425069,0.9559469,0.00170138,0.0027832,0.002776929,0.00004682234,0.0002088896,0.00001156281,0.002273528],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0031144,"threshold_uncertainty_score":0.01041871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2090904553886902,"score_gpt":0.4972978398233645,"score_spread":0.2882073844346743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}