{"id":"W2591377221","doi":"10.1182/blood.v128.22.3280.3280","title":"Mutational Characterisation and Tracking Disease Progression Using Circulating Cell-Free Tumor DNA in Multiple Myeloma Patients","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Collège Boréal","funders":"","keywords":"Neuroblastoma RAS viral oncogene homolog; Monoclonal gammopathy of undetermined significance; Digital polymerase chain reaction; KRAS; Cell-free fetal DNA; Liquid biopsy; Multiple myeloma; Medicine; GNAS complex locus; Cancer research; Bone marrow; Pathology; Monoclonal; Oncology; Internal medicine; Biology; Cancer; Immunology; Polymerase chain reaction; Gene; Colorectal cancer; Monoclonal antibody; Antibody; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003865462,0.00026595,0.0003408912,0.000966904,0.0002408784,0.0005135405,0.0002483466,0.0004774443,0.001309503],"category_scores_gemma":[0.001075128,0.0001476455,0.0001338548,0.0005701265,0.000151233,0.0002614564,0.0002922016,0.0003689665,0.0003074155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003285692,"about_ca_system_score_gemma":0.0001580157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130144,"about_ca_topic_score_gemma":0.001058873,"domain_scores_codex":[0.9997014,0.00004498252,0.00002826237,0.0001152996,0.00008304167,0.00002691237],"domain_scores_gemma":[0.9996531,0.0001007636,0.00009790612,0.00002211409,0.0000662957,0.00005980642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002449009,0.0001467321,0.857682,0.0002105591,0.0000949571,0.0008306361,0.0005238119,0.0007197274,0.09612812,0.00009784671,0.0004877712,0.04062881],"study_design_scores_gemma":[0.00007997207,0.00177825,0.9510134,0.00004958055,0.0001348088,0.0042396,0.0002610068,0.003085055,0.03602883,0.0001510286,0.003160177,0.00001834948],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973563,0.0009986683,0.0006851202,0.00004123108,0.000005575813,0.00001734154,0.0004792003,0.00003493655,0.000381667],"genre_scores_gemma":[0.9980937,0.0001604969,0.0009228655,0.00003777534,0.00000692787,0.00001413488,0.0004305058,0.000005874624,0.0003276957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001309503,"threshold_uncertainty_score":0.004380763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01127584999793887,"score_gpt":0.2322381915251035,"score_spread":0.2209623415271646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}