{"id":"W2591387482","doi":"10.1182/blood.v116.21.3625.3625","title":"The Epstein-Barr Virus (EBV) Encoded Oncoprotein LMP1 Mediates Down Regulation of Shelterin Proteins, Formation of Telomere Aggregates and Multinuclearity.","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Université de Sherbrooke","funders":"","keywords":"Shelterin; Telomere; Biology; Transfection; Cell culture; Molecular biology; Lymphoma; Germinal center; Cancer research; Virology; B cell; Immunology; Genetics; DNA; Gene; Antibody; Transcription factor; DNA-binding protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007395364,0.0001982515,0.0001124778,0.000102468,0.0001108634,0.0001699991,0.0001306149,0.0001790946,0.001069175],"category_scores_gemma":[0.00007147039,0.0001058965,0.0001282302,0.0000809776,0.0001577255,0.0001388111,0.0002231905,0.0002780416,0.0003821232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001814901,"about_ca_system_score_gemma":0.0000849122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004062723,"about_ca_topic_score_gemma":0.0006680675,"domain_scores_codex":[0.9999367,0.00001101499,0.000005793514,0.00001531874,0.00001602976,0.00001511731],"domain_scores_gemma":[0.9999102,0.00002329435,0.00002799941,0.0000119687,0.000006410635,0.00001999275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002564009,0.000004424306,0.00007738371,0.00001142651,7.505416e-7,0.00002013272,0.000005359872,0.000006889712,0.9996622,0.00001542179,0.00000681088,0.0001637638],"study_design_scores_gemma":[0.000006225537,0.0001048568,0.01342225,0.000003451037,0.000004524853,0.0001761685,0.00002580989,0.000430386,0.9846785,0.00001875972,0.001127093,0.000001850607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970394,0.001094858,0.0009429929,0.00002948333,0.000009695182,0.00000815068,0.000262843,0.0000412247,0.0005713059],"genre_scores_gemma":[0.9963916,0.00046411,0.000705165,0.00001328471,0.000003198938,0.00002468166,0.0005353504,0.00001198576,0.001850553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001069175,"threshold_uncertainty_score":0.003576815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006714259740301701,"score_gpt":0.2283339881522238,"score_spread":0.2216197284119221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}