{"id":"W2591666318","doi":"10.1101/gad.292516.116","title":"ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair","year":2017,"lang":"en","type":"article","venue":"Genes & Development","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Division of Chemistry; Sun Yat-sen University Cancer Center; Cancer Prevention and Research Institute of Texas; Sun Yat-sen University; Welch Foundation; Canadian Institutes of Health Research; American Cancer Society; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Chromatin; Biology; DNA repair; Histone; Cell biology; DNA damage; Nucleosome; Chromatin remodeling; DNA; Genetics; ChIA-PET; Histone code; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006622616,0.0002638529,0.000146432,0.0002073949,0.0001997411,0.0003250185,0.0002311165,0.0002199624,0.001171172],"category_scores_gemma":[0.00008345385,0.0001184544,0.0002412809,0.0001383613,0.0001959183,0.0001673622,0.0003174719,0.000359319,0.0003839523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000535035,"about_ca_system_score_gemma":0.0002584217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001226961,"about_ca_topic_score_gemma":0.002304951,"domain_scores_codex":[0.9999331,0.000005939497,0.000003821925,0.0000195273,0.00001844203,0.00001909511],"domain_scores_gemma":[0.9999163,0.000007569818,0.00003506579,0.000005278162,0.0000104914,0.00002533433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000639329,0.000005244259,0.0004361918,0.00002000589,0.000003268845,0.0000472285,0.000007680773,0.00004755387,0.9981728,0.0001073086,0.00004278026,0.001046146],"study_design_scores_gemma":[0.00002015957,0.00005256082,0.02718824,0.000007031822,0.0000153589,0.0002814246,0.00004919654,0.001369017,0.9671465,0.0001569847,0.003706993,0.000006567725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888875,0.002109977,0.005884369,0.0001911227,0.00002607278,0.00001612365,0.0008481362,0.0002400533,0.001796734],"genre_scores_gemma":[0.9954835,0.0004848534,0.00192526,0.00006029131,0.000004651907,0.000008456516,0.0004801308,0.00003767203,0.001515306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001226961,"threshold_uncertainty_score":0.003917933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100805138529474,"score_gpt":0.2435312340190003,"score_spread":0.2325231826337056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}