{"id":"W2591701973","doi":"10.1002/jcp.25891","title":"Swelling‐induced chloride current in glioblastoma proliferation, migration, and invasion","year":2017,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Viability assay; U87; Protein kinase B; PI3K/AKT/mTOR pathway; Cancer research; Cell growth; Apoptosis; Chemistry; STAT3; MTT assay; Phosphorylation; Cell culture; Cell migration; Cell biology; Glioblastoma; Molecular biology; Cell; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417153,0.00009136092,0.0001495828,0.00008334834,0.0001254967,0.00003149121,0.0001148045,0.0001041722,0.000007685507],"category_scores_gemma":[0.0001313913,0.00007785281,0.00005592373,0.00002553182,0.00004875808,0.00001928555,0.00004252247,0.0001219961,0.000002355291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001131152,"about_ca_system_score_gemma":0.00005882539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004999948,"about_ca_topic_score_gemma":0.00004004861,"domain_scores_codex":[0.9993066,0.00005787011,0.0002994041,0.0001419606,0.00008847757,0.0001057473],"domain_scores_gemma":[0.9991953,0.000006968987,0.0003962581,0.000179592,0.000169295,0.00005258793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003876092,0.00005186795,0.002541824,0.00001346303,0.00001130229,0.000002010308,0.00006413541,0.0002003266,0.9948341,0.000080473,0.0002339871,0.001578923],"study_design_scores_gemma":[0.001059911,0.0006391241,0.03064978,0.00003524283,0.00001024988,0.00003327224,0.00003655842,0.001179878,0.9555656,0.0007591848,0.009912187,0.0001190509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968408,0.0003358353,0.001469059,0.0003359058,0.0009108103,0.00007928158,6.489448e-7,0.000001669032,0.00002604162],"genre_scores_gemma":[0.9982222,0.0004185413,0.0000404922,0.00004592648,0.001195308,0.000002684091,0.00001001348,0.00000789837,0.00005698675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03926852,"threshold_uncertainty_score":0.3174745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852773703420394,"score_gpt":0.2616842312900346,"score_spread":0.2431564942558307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}