{"id":"W2591702058","doi":"10.21037/atm.2017.01.50","title":"Exosomes, your body’s answer to immune health","year":2017,"lang":"en","type":"letter","venue":"Annals of Translational Medicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Killam Trusts","keywords":"Microvesicles; CD80; Cell biology; Immune system; CD86; Exosome; Mesenchymal stem cell; CD40; CD81; Paracrine signalling; Major histocompatibility complex; Biology; Secretion; Stromal cell; Chemistry; Immunology; T cell; Cancer research; Cytotoxic T cell; Biochemistry; Receptor; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001145355,0.0004922678,0.0006626883,0.00031838,0.001520772,0.002092161,0.0005857431,0.008829823,0.01284111],"category_scores_gemma":[0.007227181,0.0001675458,0.000450284,0.000232215,0.002241576,0.003478234,0.001622891,0.01298851,0.006841023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001434703,"about_ca_system_score_gemma":0.001175732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00034001,"about_ca_topic_score_gemma":0.000611229,"domain_scores_codex":[0.9992587,0.0002609471,0.00005054173,0.0001012369,0.0002422967,0.0000862587],"domain_scores_gemma":[0.9980635,0.001054137,0.0001817235,0.0001030083,0.0002597137,0.0003378953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001171386,0.00005542333,0.0006494148,0.0003184651,0.00002805404,0.003174711,0.000217326,0.00005714276,0.001392514,0.02397883,0.8913329,0.07867803],"study_design_scores_gemma":[0.00004261641,0.00004860338,0.0002582196,0.000277556,0.00001530807,0.003702075,0.0002068854,0.0001067474,0.0003702559,0.01716998,0.9777871,0.00001471676],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001141488,0.06583642,0.0007199094,0.8531988,0.06783,0.00001865473,0.00005747234,0.00009296515,0.01110428],"genre_scores_gemma":[0.02961625,0.06257082,0.001235848,0.694794,0.1710034,0.00005940762,0.00007630941,0.00007297393,0.04057095],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01284111,"threshold_uncertainty_score":0.04295778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07437154360574628,"score_gpt":0.3798232176057388,"score_spread":0.3054516739999926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}