{"id":"W2591702058","doi":"10.21037/atm.2017.01.50","title":"Exosomes, your body’s answer to immune health","year":2017,"lang":"en","type":"letter","venue":"Annals of Translational Medicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Killam Trusts","keywords":"Microvesicles; CD80; Cell biology; Immune system; CD86; Exosome; Mesenchymal stem cell; CD40; CD81; Paracrine signalling; Major histocompatibility complex; Biology; Secretion; Stromal cell; Chemistry; Immunology; T cell; Cancer research; Cytotoxic T cell; Biochemistry; Receptor; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004177773,0.0003250788,0.0005621767,0.0001485541,0.0001060321,0.00001011473,0.0006490466,0.0004462478,0.0002189112],"category_scores_gemma":[0.0002145092,0.0002991748,0.000229342,0.00005985589,0.0002479552,0.000005549904,0.00004954232,0.0004277217,0.00001977136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005786939,"about_ca_system_score_gemma":0.0003274945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006890124,"about_ca_topic_score_gemma":0.000006490285,"domain_scores_codex":[0.9977099,0.0001047942,0.0006425633,0.0005162809,0.0006297163,0.0003967416],"domain_scores_gemma":[0.998085,0.00003346753,0.0004126055,0.000976694,0.0002994598,0.0001927425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009724487,0.0000562953,0.00009226129,0.0002907425,0.0002174384,0.00004688809,0.00007876877,0.00001059196,0.0473487,0.00002846322,0.9494549,0.00227768],"study_design_scores_gemma":[0.0005769711,0.0006002936,0.002874219,0.0004964485,0.00005070963,0.00001500161,0.000007070785,0.000005227629,0.01188524,0.0004623807,0.982729,0.0002974319],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002896326,0.025638,0.0006374746,0.9675939,0.0004407706,0.0004559995,0.0004418904,0.00001190107,0.001883708],"genre_scores_gemma":[0.1391979,0.001849465,0.001265658,0.8248744,0.01361638,0.00005707244,0.01036081,0.0001518798,0.00862638],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1427195,"threshold_uncertainty_score":0.9999461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07437154360574628,"score_gpt":0.3798232176057388,"score_spread":0.3054516739999926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}