{"id":"W2591971201","doi":"10.1016/j.ejcb.2017.03.004","title":"Incretin hormones regulate microglia oxidative stress, survival and expression of trophic factors","year":2017,"lang":"en","type":"article","venue":"European Journal of Cell Biology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"National Institutes of Health; Crohn's and Colitis Canada; Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Microglia; Incretin; Internal medicine; Endocrinology; Neurotrophic factors; Neurotrophin; Biology; Glial cell line-derived neurotrophic factor; Growth factor; Downregulation and upregulation; Nerve growth factor; Hormone; Receptor; Gastric inhibitory polypeptide; Brain-derived neurotrophic factor; Cell biology; Glucagon; Inflammation; Diabetes mellitus; Medicine; Type 2 diabetes; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003520234,0.0001154808,0.0003332252,0.00008434087,0.00006997278,0.0000152155,0.0001568939,0.00002551266,0.00003246415],"category_scores_gemma":[0.00006867643,0.0000729509,0.00007580561,0.00001502313,0.0001983629,0.00006296405,0.0001321674,0.0001070891,0.000004420892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008786299,"about_ca_system_score_gemma":0.00001147361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000045336,"about_ca_topic_score_gemma":5.273134e-7,"domain_scores_codex":[0.9991574,0.0002345481,0.0002967371,0.0001103732,0.0000731595,0.0001278316],"domain_scores_gemma":[0.9989101,0.00004245935,0.0006666597,0.0002144741,0.0000808903,0.00008540705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003005988,0.0001021011,0.08833314,0.00004181991,0.000103329,0.0001134302,0.0002017722,4.555472e-7,0.9068639,0.00003268114,0.0002198103,0.003686907],"study_design_scores_gemma":[0.002415807,0.001910927,0.4218447,0.0001399035,0.0001626618,0.000005320076,0.0002216731,0.000001588555,0.5696294,0.00004176047,0.003545358,0.00008093756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901742,0.0007329055,0.00002363584,0.0001693281,0.0001823204,0.00007739451,0.000008167387,0.000004184594,0.008627868],"genre_scores_gemma":[0.9981268,0.0005896048,0.0006080196,0.00001137768,0.00009647669,1.400227e-7,0.000009464267,0.00001318934,0.0005449448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3372346,"threshold_uncertainty_score":0.2974851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01859420031906367,"score_gpt":0.2479468991823897,"score_spread":0.2293526988633261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}