{"id":"W2592081749","doi":"10.1182/blood.v120.21.980.980","title":"Dyskerin Is Upregulated During Erythroid Differentiation of Human Hematopoietic Progenitor Cells and Hyperactivates Telomerase in Erythroid Precursor Cells","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre","funders":"","keywords":"Telomerase; Telomerase reverse transcriptase; Biology; Telomere; Telomerase RNA component; Haematopoiesis; Cellular differentiation; Molecular biology; Myeloid; Myeloid leukemia; Stem cell; Progenitor cell; CD34; Cancer research; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008273414,0.0001457398,0.0001934196,0.0003904722,0.0001547399,0.0002901495,0.00007647393,0.0001832109,0.001854164],"category_scores_gemma":[0.0001025728,0.0001352095,0.00009607438,0.0002693946,0.0001122329,0.0001173297,0.0002046768,0.0002556562,0.0005280028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001483856,"about_ca_system_score_gemma":0.0001036479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003486817,"about_ca_topic_score_gemma":0.000451953,"domain_scores_codex":[0.9998848,0.00001523975,0.00001336378,0.00002425469,0.00003458083,0.00002770882],"domain_scores_gemma":[0.9998902,0.0000212486,0.00002353619,0.00001233524,0.00001795477,0.00003476219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007239041,0.00001000628,0.0009209914,0.00001801354,0.000003000501,0.0001120943,0.00001488087,0.000008596462,0.9982097,0.00002195182,0.00001891542,0.0005894293],"study_design_scores_gemma":[0.00002084806,0.0001774661,0.1466957,0.000007558405,0.00002296863,0.001181047,0.0001192972,0.0003961751,0.8484715,0.00004570486,0.002857168,0.000004672466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965121,0.001265063,0.0004930068,0.00002854477,0.000008266019,0.0000163584,0.0003459304,0.00004179488,0.001288944],"genre_scores_gemma":[0.9955769,0.0005742643,0.0004566242,0.00002531295,0.000007377033,0.00002962261,0.0006035233,0.000008156315,0.002718237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001854164,"threshold_uncertainty_score":0.006202757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105278210481861,"score_gpt":0.2418184215624164,"score_spread":0.2307656394575978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}