{"id":"W2592143294","doi":"10.1182/blood.v108.11.388.388","title":"Deregulated Expression of a Novel Oncogene, Ahi-1, in Murine Hematopoietic Cells Confers a Proliferative Advantage In Vitro and Leukemogenic Activity In Vivo and Enhances the Effects of BCR-ABL.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Haematopoiesis; Cancer research; Biology; Myeloid; breakpoint cluster region; CD34; Myeloid leukemia; K562 cells; Leukemia; Stem cell; Immunology; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001487643,0.0004214662,0.0001584329,0.0003097184,0.0001237298,0.0002708807,0.0001609893,0.0002545837,0.0008678801],"category_scores_gemma":[0.00007261054,0.0001171085,0.0001934964,0.0001585964,0.0002258238,0.0001482292,0.0001848744,0.0006583664,0.0002679062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003027869,"about_ca_system_score_gemma":0.00015996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002361392,"about_ca_topic_score_gemma":0.0003188675,"domain_scores_codex":[0.999841,0.00002532399,0.00001642156,0.00002761822,0.00004444224,0.00004515911],"domain_scores_gemma":[0.9998749,0.00002588974,0.00004163037,0.00001415967,0.00000782093,0.00003557202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002555831,0.00001196389,0.00005714216,0.000006040802,9.602303e-7,0.00001117375,0.000003829309,0.00002562934,0.999566,0.00004597746,0.000005163017,0.0002405839],"study_design_scores_gemma":[0.000008838636,0.0002283505,0.001596993,0.00000222917,0.000007073242,0.0001137463,0.000009270658,0.0004385623,0.9967526,0.00002134716,0.0008192797,0.000001788769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971073,0.0006516863,0.001259103,0.00004473565,0.00001482308,0.00002042261,0.0003006971,0.00005485248,0.0005462516],"genre_scores_gemma":[0.9965,0.0003619512,0.001262399,0.00001767138,0.000007661856,0.00002368746,0.0005859235,0.0000128288,0.001227927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008678801,"threshold_uncertainty_score":0.002903342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005231381339900623,"score_gpt":0.232767478647267,"score_spread":0.2275360973073664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}