{"id":"W2592186978","doi":"10.1055/s-0037-1599141","title":"4H Leukodystrophy: A Brain Magnetic Resonance Imaging Scoring System","year":2017,"lang":"en","type":"article","venue":"Neuropediatrics","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital; McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; University College London Hospitals NHS Foundation Trust; National Institute for Health and Care Research","keywords":"Medicine; Leukodystrophy; Magnetic resonance imaging; Neuroimaging; Nuclear magnetic resonance; Radiology; Pathology; Psychiatry; Disease; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001007047,0.0001313394,0.00009351686,0.00003968062,0.000311044,0.0002074984,0.0003525626,0.0000424089,0.000006508405],"category_scores_gemma":[0.0003023738,0.0001338996,0.00007374734,0.00004549332,0.00005812534,0.00001226019,0.000194895,0.00006777787,0.00003714453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001305429,"about_ca_system_score_gemma":0.00006410007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001674548,"about_ca_topic_score_gemma":0.000002518776,"domain_scores_codex":[0.9990672,0.00004699732,0.0001613423,0.0003435304,0.0001567797,0.0002241381],"domain_scores_gemma":[0.9989108,0.000008675235,0.0001194335,0.0007532612,0.00007060384,0.0001372225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002871011,0.0001109218,0.6597427,0.0002159846,0.000008300293,0.0005124339,0.00004862225,0.000248981,0.2118931,0.0007511422,0.01993359,0.1062471],"study_design_scores_gemma":[0.001764209,0.0001737626,0.8299811,0.00002707297,0.00004660818,0.00006781653,0.00005564098,0.002823584,0.002418435,0.000007408367,0.1621465,0.0004879195],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874162,0.003264998,0.0004502326,0.0003011452,0.0005351279,0.0001499861,0.00001214807,0.0000458601,0.007824316],"genre_scores_gemma":[0.9969149,0.0001147682,0.0002474153,0.0003439364,0.0008165757,0.000008307861,0.00001122579,0.00003183782,0.001511006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2094747,"threshold_uncertainty_score":0.5460266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008630854543458792,"score_gpt":0.2336552217771582,"score_spread":0.2250243672336994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}