{"id":"W2592274279","doi":"10.1186/s40425-017-0223-8","title":"Systematic evaluation of immune regulation and modulation","year":2017,"lang":"en","type":"review","venue":"Journal for ImmunoTherapy of Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; U.S. National Library of Medicine; National Cancer Institute; National Institutes of Health; Trent University; Sidra Medicine; Nottingham Trent University","keywords":"Immune system; Immunotherapy; Medicine; Computational biology; Tumor microenvironment; Identification (biology); Cancer immunotherapy; Task force; Cancer; Bioinformatics; Computer science; Immunology; Data science; Biology; Internal medicine; Political science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00418612,0.0008746139,0.002356804,0.002519149,0.0002075761,0.001447711,0.001034358,0.001148076,0.00160006],"category_scores_gemma":[0.005680413,0.0002843387,0.00137678,0.001932376,0.0005830953,0.001360379,0.0007325236,0.001114885,0.0005107828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008054632,"about_ca_system_score_gemma":0.003451816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001014018,"about_ca_topic_score_gemma":0.001972594,"domain_scores_codex":[0.9978794,0.0007837749,0.000371551,0.000237147,0.0006485269,0.00007962345],"domain_scores_gemma":[0.9969997,0.001656249,0.0003928282,0.0001266152,0.0007712297,0.00005334503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001714887,0.00009246809,0.0008436914,0.1002373,0.0007997121,0.0001156755,0.0001030656,0.0004040227,0.00317494,0.003894636,0.009672943,0.8804901],"study_design_scores_gemma":[0.0001451744,0.0007829273,0.006747405,0.06453133,0.003726033,0.001525649,0.0002688275,0.0004097446,0.007531507,0.004584113,0.9096693,0.00007800203],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002785021,0.9983923,0.0002788093,0.0002843422,0.0001390668,0.0000325996,0.00004255295,0.000004421822,0.0005473637],"genre_scores_gemma":[0.00344394,0.9949523,0.0007820757,0.0003403263,0.0001198019,0.00006480763,0.00006766089,0.00000221474,0.0002269695],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00418612,"threshold_uncertainty_score":0.0221386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1355874660510514,"score_gpt":0.4619861904541074,"score_spread":0.326398724403056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}