{"id":"W2592294322","doi":"10.1001/jamaoncol.2016.5945","title":"Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases","year":2017,"lang":"en","type":"article","venue":"JAMA Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":529,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; University of Toronto; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Health and Medical Research Council; National Center for Advancing Translational Sciences; Medical Research Council; National Heart, Lung, and Blood Institute; Anschutz Medical Campus, University of Colorado; Health Research Council of New Zealand; University of Texas Health Science Center at San Antonio; University of California, San Diego; National Institutes of Health; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Vincent Fairfax Family Foundation; World Health Organization; Wellcome Trust; Cancer Research UK; Morehouse School of Medicine; Johns Hopkins University; National Jewish Health; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institute of Neurological Disorders and Stroke; British Heart Foundation; University of Pittsburgh; University of Minnesota; Brigham and Women's Hospital; Canadian Institutes of Health Research; Cancerfonden; NHLBI Division of Intramural Research; Motor Neurone Disease Association; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Temple University; South London and Maudsley NHS Foundation Trust; Deutsche Forschungsgemeinschaft; National Cancer Institute; University of Bristol; GlaxoSmithKline; King's College London; World Cancer Research Fund; American Heart Association","keywords":"Medicine; Telomere; Cancer; Oncology; Internal medicine; Genetics; DNA; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963649,0.0001206213,0.0004930815,0.00007357159,0.0002052261,0.00002670187,0.00008328213,0.0002118727,0.00003770372],"category_scores_gemma":[0.001402523,0.0001016573,0.00004143278,0.0000401061,0.0002005919,0.0001200121,0.00008337881,0.0002156602,0.000005314531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001268017,"about_ca_system_score_gemma":0.0001795421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001653431,"about_ca_topic_score_gemma":0.001056332,"domain_scores_codex":[0.9991029,0.00005614469,0.000225392,0.0002369704,0.0001601175,0.0002184729],"domain_scores_gemma":[0.9983855,0.0006301088,0.0004483892,0.0002443633,0.0001169513,0.0001746619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001198643,0.00005433791,0.8726654,0.000106127,0.0002394835,0.00001704779,0.0002205833,3.280885e-7,0.0003545087,0.00001098643,0.001268318,0.124943],"study_design_scores_gemma":[0.002332053,0.0004115118,0.9873432,0.00008387933,0.0008715189,0.000006100528,0.0001007782,0.00007372987,0.0004659336,0.00009744408,0.008114906,0.00009894622],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954464,0.00129514,0.00001182475,0.001774033,0.0002032383,0.0001983763,0.0001705846,0.00001818568,0.0008821483],"genre_scores_gemma":[0.9929379,0.005736412,0.0001776559,0.0001224775,0.0004348602,0.00001645373,0.00001033547,0.00001260607,0.0005513226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1248441,"threshold_uncertainty_score":0.4145465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01448770962222359,"score_gpt":0.3185083507505348,"score_spread":0.3040206411283112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}