{"id":"W2592294322","doi":"10.1001/jamaoncol.2016.5945","title":"Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases","year":2017,"lang":"en","type":"article","venue":"JAMA Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":529,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Public Health Ontario; University of Toronto; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Health and Medical Research Council; National Center for Advancing Translational Sciences; Medical Research Council; National Heart, Lung, and Blood Institute; Anschutz Medical Campus, University of Colorado; Health Research Council of New Zealand; University of Texas Health Science Center at San Antonio; University of California, San Diego; National Institutes of Health; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; Vincent Fairfax Family Foundation; World Health Organization; Wellcome Trust; Cancer Research UK; Morehouse School of Medicine; Johns Hopkins University; National Jewish Health; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institute of Neurological Disorders and Stroke; British Heart Foundation; University of Pittsburgh; University of Minnesota; Brigham and Women's Hospital; Canadian Institutes of Health Research; Cancerfonden; NHLBI Division of Intramural Research; Motor Neurone Disease Association; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Temple University; South London and Maudsley NHS Foundation Trust; Deutsche Forschungsgemeinschaft; National Cancer Institute; University of Bristol; GlaxoSmithKline; King's College London; World Cancer Research Fund; American Heart Association","keywords":"Medicine; Telomere; Cancer; Oncology; Internal medicine; Genetics; DNA; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006663539,0.0002790592,0.0004582908,0.001509092,0.0002128565,0.0005558581,0.0005610759,0.0004330152,0.002740161],"category_scores_gemma":[0.030562,0.0001936095,0.001312557,0.002659023,0.0005579686,0.0005553029,0.0005240164,0.0006396787,0.0001501301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003311627,"about_ca_system_score_gemma":0.0006625727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001739572,"about_ca_topic_score_gemma":0.002185056,"domain_scores_codex":[0.9950621,0.002309813,0.000850035,0.0009426328,0.0007095477,0.0001258747],"domain_scores_gemma":[0.9693637,0.0168446,0.01058562,0.001932188,0.0008974074,0.0003764262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009291635,0.00002953089,0.9771287,0.001008097,0.003173209,0.00008534216,0.00008584556,0.0006445863,0.00078983,0.0004732237,0.0003782628,0.01527429],"study_design_scores_gemma":[0.0001024149,0.0004087749,0.9918275,0.0002772041,0.001870982,0.0004440689,0.00007980188,0.001088548,0.0006559114,0.001633917,0.001589759,0.00002107841],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9442385,0.02953041,0.01211113,0.001713825,0.000177092,0.0001725324,0.008858738,0.0001049969,0.003092855],"genre_scores_gemma":[0.9924936,0.002659259,0.002829192,0.0001311694,0.00008937072,0.0000569866,0.001502326,0.00001139465,0.0002266644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006663539,"threshold_uncertainty_score":0.03524065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01448770962222359,"score_gpt":0.3185083507505348,"score_spread":0.3040206411283112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}