{"id":"W2592318296","doi":"10.1080/2162402x.2017.1299303","title":"Immune biomarkers for prognosis and prediction of responses to immune checkpoint blockade in cutaneous melanoma","year":2017,"lang":"en","type":"review","venue":"OncoImmunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Immune system; Medicine; Melanoma; Immune checkpoint; Adjuvant; Immunotherapy; Blockade; Immunology; Cancer research; Internal medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001208382,0.0004847424,0.00326184,0.001232171,0.0001102364,0.00002696676,0.0004694347,0.0008568232,0.0002205755],"category_scores_gemma":[0.00130613,0.0004190546,0.0005987667,0.0003354124,0.0004726381,0.00004449091,0.0003272492,0.0006384695,0.00001877746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004614953,"about_ca_system_score_gemma":0.0008301444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004296444,"about_ca_topic_score_gemma":0.00003551473,"domain_scores_codex":[0.9966251,0.0003808589,0.001444764,0.000684263,0.0002498708,0.0006151586],"domain_scores_gemma":[0.9970293,0.0008056698,0.0006531621,0.001215859,0.0001876944,0.0001083185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003800987,0.0002562347,0.0001970956,0.008207562,0.001316714,0.0001348232,0.0002095602,3.190187e-8,0.03012276,0.00000774761,0.00002928582,0.9557172],"study_design_scores_gemma":[0.002313922,0.004167934,0.002239767,0.01219574,0.0007824998,0.002442824,0.00008482823,0.000005877857,0.001704348,0.00001955884,0.9737584,0.0002842885],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009614294,0.9832396,0.000005682472,0.0004290832,0.0003508463,0.005336236,0.0002311287,0.00004722079,0.0007458963],"genre_scores_gemma":[0.001243958,0.9903524,0.0005357215,0.000006560516,0.0001050376,0.001358977,0.0002018754,0.0001179343,0.006077535],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9737291,"threshold_uncertainty_score":0.9998261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09316718438393705,"score_gpt":0.3941380399412248,"score_spread":0.3009708555572877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}