{"id":"W2592318296","doi":"10.1080/2162402x.2017.1299303","title":"Immune biomarkers for prognosis and prediction of responses to immune checkpoint blockade in cutaneous melanoma","year":2017,"lang":"en","type":"review","venue":"OncoImmunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Immune system; Medicine; Melanoma; Immune checkpoint; Adjuvant; Immunotherapy; Blockade; Immunology; Cancer research; Internal medicine; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001093449,0.0009198998,0.001919529,0.002900303,0.000157848,0.0009342943,0.0009005093,0.001100914,0.001561805],"category_scores_gemma":[0.001768317,0.000274729,0.0008171689,0.001741844,0.0004857719,0.0009386524,0.0005940526,0.00174862,0.0008089658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005842583,"about_ca_system_score_gemma":0.0007787117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001075312,"about_ca_topic_score_gemma":0.001462167,"domain_scores_codex":[0.9996736,0.00007788635,0.00006208842,0.00005409156,0.0001099427,0.00002231481],"domain_scores_gemma":[0.9992666,0.0004230337,0.0001101851,0.00001581871,0.000156008,0.00002838787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001020378,0.00006055633,0.0007196837,0.01224368,0.0002206166,0.000128847,0.00003495782,0.0003407101,0.0006713188,0.001509214,0.01382112,0.9701474],"study_design_scores_gemma":[0.00009522747,0.0003558277,0.008570914,0.02613043,0.001428311,0.003860177,0.0001804193,0.0007137185,0.001566753,0.005654247,0.951349,0.00009499689],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008313057,0.9994439,0.00006622358,0.0001240442,0.00006714519,0.000002812188,0.00001125238,0.000002948272,0.0001983634],"genre_scores_gemma":[0.001239988,0.9981116,0.0001795636,0.0001235297,0.0001222388,0.000007435631,0.00002967877,9.942797e-7,0.0001849349],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002900303,"threshold_uncertainty_score":0.005782783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09316718438393705,"score_gpt":0.3941380399412248,"score_spread":0.3009708555572877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}