{"id":"W2592332357","doi":"10.1182/blood.v128.22.2248.2248","title":"Radius: A Phase 2, Randomized Trial of Standard of Care (SOC) with or without Midostaurin to Prevent Relapse Following Allogeneic Hematopoietic Stem Cell Transplant (alloHSCT) in Patients (pts) with FLT3-Itd-Mutated Acute Myeloid Leukemia (AML)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Midostaurin; Medicine; Internal medicine; Oncology; Adverse effect; Maintenance therapy; Clinical endpoint; Phases of clinical research; Randomized controlled trial; Clinical trial; Chemotherapy; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001511928,0.001770045,0.002089115,0.0004367278,0.0003372342,0.001050322,0.0009081868,0.001423017,0.008158668],"category_scores_gemma":[0.001340241,0.000607426,0.00189368,0.0002810323,0.0009944385,0.0009430728,0.0005437588,0.002640422,0.001361138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000693172,"about_ca_system_score_gemma":0.001107152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006233631,"about_ca_topic_score_gemma":0.002262449,"domain_scores_codex":[0.9992866,0.0004117108,0.00004249685,0.0001235091,0.00004574425,0.0000899088],"domain_scores_gemma":[0.9993485,0.0001465007,0.0001787291,0.00005261888,0.00004449662,0.0002291083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9696335,0.007005517,0.0004402635,0.0008754912,0.0007489013,0.00004176669,0.00005602625,0.00034175,0.004557959,0.0002020889,0.001088096,0.01500863],"study_design_scores_gemma":[0.9237068,0.07384507,0.0007541666,0.00003075161,0.0003612023,0.00004266614,0.00001757633,0.0002523349,0.0003026211,0.0001218505,0.0005536938,0.00001137809],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804938,0.004576817,0.000769388,0.0009093206,0.0005674372,0.007494448,0.001652628,0.0002741073,0.003262043],"genre_scores_gemma":[0.9753567,0.003134056,0.003137245,0.001858698,0.0004644804,0.009078756,0.001783104,0.00003856989,0.005148277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008158668,"threshold_uncertainty_score":0.02729344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008505898755819464,"score_gpt":0.2653194782138638,"score_spread":0.2568135794580443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}