{"id":"W2592332357","doi":"10.1182/blood.v128.22.2248.2248","title":"Radius: A Phase 2, Randomized Trial of Standard of Care (SOC) with or without Midostaurin to Prevent Relapse Following Allogeneic Hematopoietic Stem Cell Transplant (alloHSCT) in Patients (pts) with FLT3-Itd-Mutated Acute Myeloid Leukemia (AML)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Midostaurin; Medicine; Internal medicine; Oncology; Adverse effect; Maintenance therapy; Clinical endpoint; Phases of clinical research; Randomized controlled trial; Clinical trial; Chemotherapy; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001023121,0.0006101636,0.002825333,0.0005471354,0.00006252433,0.00001746934,0.0004095259,0.0002531658,0.00005078413],"category_scores_gemma":[0.0001375395,0.0003274934,0.0003968648,0.0007847642,0.0002516761,0.0001596201,0.00008554992,0.0003778411,0.000006606901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008936757,"about_ca_system_score_gemma":0.002552768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001284268,"about_ca_topic_score_gemma":0.0001889167,"domain_scores_codex":[0.9947092,0.0005713267,0.001437519,0.0008271972,0.00162501,0.0008297334],"domain_scores_gemma":[0.9971281,0.0004613155,0.0004887778,0.0008851512,0.000546054,0.000490636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.949281,0.002816277,0.004973071,0.0009092721,0.00184876,0.0007508022,0.009490928,0.00001421523,0.02871817,0.000004066237,0.00004226807,0.001151219],"study_design_scores_gemma":[0.6942453,0.01792745,0.00005025574,0.002689356,0.002193652,0.00003912965,0.0006942771,0.000006717209,0.281767,0.00000211635,0.00004703959,0.0003377695],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894258,0.000300912,0.0004761506,0.0001164766,0.00008991457,0.008999483,0.0003483073,0.00006948379,0.0001734861],"genre_scores_gemma":[0.9962552,0.0002223728,0.002060893,0.00003925894,0.00005232949,0.0005408548,0.00008882576,0.0001442324,0.000596096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2550357,"threshold_uncertainty_score":0.9999177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008505898755819464,"score_gpt":0.2653194782138638,"score_spread":0.2568135794580443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}