{"id":"W2592535678","doi":"10.1016/j.jid.2017.02.977","title":"TNF-α Antagonist and Vascular Inflammation in Patients with Psoriasis Vulgaris: A Randomized Placebo-Controlled Study","year":2017,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lynde Centre for Dermatology; Université de Montréal; Montreal Heart Institute; Innovaderm (Canada)","funders":"AbbVie Canada","keywords":"Medicine; Adalimumab; Placebo; Clinical endpoint; Psoriasis; Internal medicine; Inflammation; Randomized controlled trial; Tumor necrosis factor alpha; Gastroenterology; Pathology; Dermatology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022235,0.001979027,0.00673379,0.00070129,0.0008799885,0.001541551,0.001217255,0.003114851,0.007043366],"category_scores_gemma":[0.002348857,0.001334926,0.00295928,0.0008462105,0.002251617,0.001518346,0.0006051752,0.003358219,0.001023627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007732615,"about_ca_system_score_gemma":0.00107337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001316085,"about_ca_topic_score_gemma":0.001894409,"domain_scores_codex":[0.9986057,0.0006823455,0.0001328272,0.0002422984,0.0001165915,0.0002202812],"domain_scores_gemma":[0.9980637,0.0006040513,0.0003849036,0.0002170027,0.0001607456,0.0005695199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9883305,0.005084821,0.0005308706,0.0003268538,0.0007107127,0.00003606173,0.00002224735,0.00006078315,0.001315095,0.00001981933,0.000107215,0.003455077],"study_design_scores_gemma":[0.9407598,0.05538152,0.002334556,0.00002065223,0.0009366707,0.00002537856,0.00002253469,0.0001104984,0.000152838,0.0000452827,0.0001974174,0.00001288656],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877307,0.007230196,0.0005151597,0.0004266452,0.0005654754,0.001933004,0.0005293855,0.00007715714,0.0009923157],"genre_scores_gemma":[0.9892011,0.004307104,0.0007546929,0.0007996298,0.0009909585,0.001538047,0.0005727778,0.00001735551,0.001818412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007043366,"threshold_uncertainty_score":0.02356237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01075199453293854,"score_gpt":0.2324341759700547,"score_spread":0.2216821814371162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}