{"id":"W2592575030","doi":"10.1111/bjh.14610","title":"Large scale studies assessing anti‐factor <scp>VIII</scp> antibody development in previously untreated haemophilia A: what has been learned, what to believe and how to learn more","year":2017,"lang":"en","type":"review","venue":"British Journal of Haematology","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Haemophilia; Medicine; Clinical trial; Population; Immunogenicity; Intensive care medicine; Randomized controlled trial; Scale (ratio); Immunology; Pediatrics; Internal medicine; Antibody; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04520307,0.0007404033,0.005821088,0.0009830667,0.0003387951,0.002782876,0.001162617,0.001973093,0.003488904],"category_scores_gemma":[0.09472262,0.0005073686,0.003906263,0.002053414,0.001198711,0.002955426,0.0008647529,0.001968679,0.0005069746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008331048,"about_ca_system_score_gemma":0.003283744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001322226,"about_ca_topic_score_gemma":0.00307507,"domain_scores_codex":[0.983623,0.00915676,0.004349251,0.001031037,0.001609819,0.0002300824],"domain_scores_gemma":[0.6999205,0.2529653,0.02715764,0.005581875,0.01310209,0.001272502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00971346,0.0004994183,0.01654259,0.4293119,0.04574068,0.0002677531,0.0007758045,0.0004513993,0.002974015,0.001811801,0.006591801,0.4853195],"study_design_scores_gemma":[0.006179568,0.02508646,0.1251808,0.4689997,0.1787727,0.001878655,0.002171899,0.0005096522,0.003199128,0.008350751,0.1793778,0.0002928261],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009047992,0.9845816,0.0008753864,0.003168827,0.0008490201,0.0003634921,0.0002292933,0.00001460902,0.0008696516],"genre_scores_gemma":[0.09097826,0.8943814,0.004369071,0.006481052,0.002156282,0.0006498052,0.0005224009,0.00002891731,0.000432852],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.04520307,"threshold_uncertainty_score":0.2390596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1507678536202383,"score_gpt":0.4363540574161198,"score_spread":0.2855862037958815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}