{"id":"W2592595418","doi":"10.1182/blood.v106.11.1876.1876","title":"Biochemical and Pharmacologic Profiling of a Novel Dual Acting Antithrombin Agent with Antiprotease and Antiplatelet Actions. Hematologic Implications.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Medicure (Canada)","funders":"","keywords":"Antithrombotic; Pharmacology; Antithrombin; Argatroban; Platelet; Chemistry; Anticoagulant; Thrombin; Medicine; Heparin; Immunology; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001319458,0.0003454839,0.000182233,0.0003578617,0.0001047871,0.0002103216,0.000168711,0.0002261474,0.001384604],"category_scores_gemma":[0.00009847176,0.00008790477,0.0001917792,0.0002038851,0.00009582734,0.0001402915,0.00007348005,0.0003459263,0.0003829514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001664252,"about_ca_system_score_gemma":0.000202114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005159117,"about_ca_topic_score_gemma":0.0009096292,"domain_scores_codex":[0.9999417,0.00001219165,0.00000633421,0.000009825212,0.00001532524,0.00001454194],"domain_scores_gemma":[0.9999409,0.000006889307,0.00001482484,0.000003313359,0.00001392613,0.00002018513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000438055,0.0003026908,0.0003243517,0.0001165955,0.00001893046,0.0001536158,0.000009570136,0.0001857212,0.9881684,0.0001086358,0.0002185177,0.009954807],"study_design_scores_gemma":[0.0003750027,0.01692577,0.01060086,0.00003354986,0.0002409247,0.002051022,0.00003419302,0.00175605,0.954712,0.00009072522,0.01316365,0.0000161412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745822,0.01417096,0.003600052,0.0003126595,0.00006202416,0.000247412,0.001321665,0.00007374134,0.005629314],"genre_scores_gemma":[0.9835707,0.005100848,0.004824872,0.0002444275,0.00005576525,0.00006784064,0.002240479,0.000009195304,0.003885885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001384604,"threshold_uncertainty_score":0.004631996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05432742738575021,"score_gpt":0.3155505527129445,"score_spread":0.2612231253271943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}