{"id":"W2592614365","doi":"10.1161/atvb.33.suppl_1.a77","title":"Abstract 77: Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) Targets the CD36 Receptor for Degradation","year":2013,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"CD36; Proprotein convertase; PCSK9; Scavenger receptor; Kexin; LDL receptor; Chemistry; Biology; Protein degradation; Endocrinology; Internal medicine; Biochemistry; Lipoprotein; Cholesterol; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008799175,0.0005559368,0.0002838438,0.0002238577,0.0002472583,0.0003203792,0.0001649758,0.000334262,0.007900232],"category_scores_gemma":[0.0001161269,0.000115515,0.000376725,0.0002559459,0.0001939348,0.0002114357,0.0002514655,0.0006244135,0.003732124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004301297,"about_ca_system_score_gemma":0.000300739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009867102,"about_ca_topic_score_gemma":0.0005796775,"domain_scores_codex":[0.9998523,0.00001290011,0.0000183938,0.00003117293,0.00005123071,0.00003395994],"domain_scores_gemma":[0.9999377,0.000008357606,0.00001622683,0.000006554626,0.00001335567,0.00001786871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004187319,0.00002846025,0.0002448536,0.0001621991,0.00001144373,0.0002497619,0.0000113821,0.00005734059,0.9919783,0.0002110264,0.0006603438,0.005966153],"study_design_scores_gemma":[0.00004757575,0.0001987294,0.008317347,0.00001406132,0.00002537872,0.001260171,0.00001426939,0.0004903321,0.9711287,0.00009995227,0.01839666,0.00000683736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9317253,0.02424114,0.01602461,0.002030216,0.0008967438,0.0001354799,0.006124142,0.000725365,0.01809707],"genre_scores_gemma":[0.910449,0.01134403,0.006703025,0.0004188668,0.0002530315,0.00009959856,0.007428345,0.00009243825,0.06321168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007900232,"threshold_uncertainty_score":0.02642894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02573912815313547,"score_gpt":0.2629644941853764,"score_spread":0.2372253660322409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}