{"id":"W2592645918","doi":"10.3389/fcell.2017.00019","title":"Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes","year":2017,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; University of Toronto; Ontario Stroke Network; University Health Network","funders":"Canadian Institutes of Health Research; J.P. Bickell Foundation; Heart and Stroke Foundation of Canada","keywords":"Induced pluripotent stem cell; Cell biology; Regenerative medicine; Biology; Stem cell; Embryonic stem cell; Neuroscience; Function (biology); Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004266581,0.0006139972,0.0005546327,0.001517605,0.0001709494,0.0005045632,0.0004449229,0.0005886795,0.002123682],"category_scores_gemma":[0.0002904224,0.0002044584,0.0003997857,0.001103267,0.0002567593,0.0007684441,0.0005347303,0.0009956226,0.001627728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003095061,"about_ca_system_score_gemma":0.0005201686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002974274,"about_ca_topic_score_gemma":0.0005691604,"domain_scores_codex":[0.9998386,0.00001748704,0.0000236245,0.00002871658,0.00007729321,0.0000143968],"domain_scores_gemma":[0.9998904,0.00004499077,0.00002163755,0.00000439656,0.00002930796,0.000009192408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002890207,0.00006471871,0.0001485499,0.01717674,0.00005501596,0.0002825355,0.00009214038,0.0004599968,0.05301113,0.007187797,0.007361785,0.9141307],"study_design_scores_gemma":[0.000008594319,0.0001392872,0.0007923003,0.001880469,0.00009259859,0.00132716,0.00006545098,0.0001930846,0.02522289,0.002136092,0.9681179,0.00002416267],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008664168,0.9929328,0.002615258,0.0002101774,0.0002249732,0.00002580387,0.00004585036,0.00002477448,0.003053966],"genre_scores_gemma":[0.003580802,0.9921086,0.002093741,0.0001987411,0.0001092577,0.00003462784,0.0001013716,0.000005749497,0.001767068],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002123682,"threshold_uncertainty_score":0.007104456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1092271423672012,"score_gpt":0.2874374169521873,"score_spread":0.1782102745849862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}