{"id":"W2592703227","doi":"10.1200/jco.2013.31.15_suppl.2033","title":"Preirradiation chemotherapy with methotrexate, rituximab, and temozolomide and post-irradiation temozolomide for primary central nervous system lymphoma: RTOG 0227 phase II study results.","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cancer Care Ontario","funders":"","keywords":"Medicine; Temozolomide; Procarbazine; Primary central nervous system lymphoma; Phases of clinical research; Dacarbazine; Lomustine; Clinical endpoint; Vincristine; Radiation therapy; Regimen; Internal medicine; Chemotherapy; Surgery; Gastroenterology; Clinical trial; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0036026,0.001605993,0.002086495,0.0004187165,0.0003607057,0.0007073015,0.001252839,0.001191619,0.003260774],"category_scores_gemma":[0.001082434,0.0006276752,0.001342093,0.0004196729,0.0008236734,0.0004788823,0.0003686297,0.002433238,0.001208142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001098152,"about_ca_system_score_gemma":0.002644675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001331103,"about_ca_topic_score_gemma":0.003008637,"domain_scores_codex":[0.9989715,0.0006586737,0.00005447456,0.00009311009,0.00008492628,0.0001373945],"domain_scores_gemma":[0.9987007,0.0002545247,0.0002382175,0.0001191925,0.00008094374,0.000606387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6673259,0.1454864,0.02778729,0.001054999,0.002713563,0.0006864012,0.000362481,0.0022203,0.05253861,0.000154813,0.006461913,0.09320727],"study_design_scores_gemma":[0.5050774,0.4601186,0.02454683,0.00005410416,0.0009139407,0.0007557177,0.00004408111,0.0005509353,0.004479324,0.00006554012,0.003371512,0.00002199322],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912897,0.002673134,0.0005591342,0.0002961042,0.00005646,0.002883343,0.001115039,0.00006692168,0.001060123],"genre_scores_gemma":[0.9788033,0.002610521,0.00257127,0.001067476,0.0002102065,0.005567614,0.006769841,0.00004020932,0.002359442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0036026,"threshold_uncertainty_score":0.01905257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04520119841995056,"score_gpt":0.392990256553215,"score_spread":0.3477890581332644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}