{"id":"W2592892140","doi":"10.1182/blood.v116.21.lba-6.lba-6","title":"A Randomized Phase II Trial of Dasatinib 100 Mg Vs Imatinib 400 Mg In Newly Diagnosed Chronic Myeloid Leukemia In Chronic Phase (CML-CP): The S0325 Intergroup Trial","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Dasatinib; Internal medicine; Clinical endpoint; Imatinib; Imatinib mesylate; Randomized controlled trial; Gastroenterology; Nilotinib; Myeloid leukemia; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002371631,0.00148471,0.002459821,0.0003705017,0.0003817833,0.001046565,0.001067198,0.001396719,0.006263765],"category_scores_gemma":[0.001457158,0.0004617302,0.001422876,0.0004240983,0.001121157,0.0008324617,0.0004398528,0.002918942,0.001137397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008859108,"about_ca_system_score_gemma":0.001444619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009151302,"about_ca_topic_score_gemma":0.002494571,"domain_scores_codex":[0.9991979,0.0005466572,0.00003545294,0.0000938075,0.00004242571,0.00008376195],"domain_scores_gemma":[0.9990489,0.0002079152,0.0002160311,0.0000569231,0.00003716856,0.0004330235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9802219,0.004282317,0.000751058,0.0002895269,0.0004169778,0.00004630438,0.00003549234,0.0004150532,0.001887105,0.0001483056,0.00136553,0.01014041],"study_design_scores_gemma":[0.9566853,0.0407803,0.001224571,0.00001917325,0.0001883298,0.0000285059,0.00001731896,0.0003070234,0.0001777798,0.000115192,0.000448117,0.000008425644],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858537,0.003752207,0.0004362903,0.001383288,0.0005909004,0.00376602,0.001218394,0.0001167272,0.002882459],"genre_scores_gemma":[0.9877237,0.001740213,0.001038026,0.001795275,0.0004570363,0.003203794,0.001360759,0.00001937264,0.002661765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006263765,"threshold_uncertainty_score":0.02095437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01886127065958134,"score_gpt":0.3201389173556108,"score_spread":0.3012776466960295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}