{"id":"W2593176248","doi":"10.1016/j.eururo.2017.02.023","title":"Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair–deficient Prostate Cancer","year":2017,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":false,"ca_institutions":"Regional Municipality of Durham; BC Cancer Agency; University of British Columbia","funders":"","keywords":"Medicine; Loss of heterozygosity; Germline; Prostate cancer; Prostate; Oncology; DNA repair; Internal medicine; Cancer; Cancer research; Gynecology; DNA; Genetics; Allele; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000773815,0.0001342383,0.0002914918,0.0005120467,0.000345298,0.0008007025,0.0003276318,0.0004619666,0.001787404],"category_scores_gemma":[0.002944181,0.00009618731,0.0005748166,0.0005909754,0.0003113042,0.0006968048,0.0005548457,0.0006396314,0.0001849564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005504298,"about_ca_system_score_gemma":0.0003942987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001709481,"about_ca_topic_score_gemma":0.002727474,"domain_scores_codex":[0.9993623,0.0001473392,0.00006664581,0.00009889001,0.0001052034,0.0002196588],"domain_scores_gemma":[0.997901,0.0004005512,0.001068853,0.00007866044,0.0001149214,0.000436001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001643398,0.0002025891,0.9801983,0.00003076222,0.0002795501,0.0002951818,0.0001373924,0.0007043844,0.001223368,0.0001939388,0.0004515138,0.01463961],"study_design_scores_gemma":[0.0000143661,0.0005000683,0.9969391,0.00001119133,0.0001375717,0.0007390496,0.0002355313,0.0003245508,0.000285781,0.0002230114,0.0005782992,0.00001156755],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997363,0.0008797463,0.0001220391,0.0002003156,0.0000109111,0.000003717762,0.0003221468,0.000006277879,0.001091819],"genre_scores_gemma":[0.9993123,0.0001038506,0.00001477963,0.00003994427,0.00001019428,0.000001826743,0.0002951746,0.000003256158,0.0002185942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001787404,"threshold_uncertainty_score":0.005979419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03292710841914352,"score_gpt":0.3384234655512099,"score_spread":0.3054963571320664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}