{"id":"W2593176248","doi":"10.1016/j.eururo.2017.02.023","title":"Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair–deficient Prostate Cancer","year":2017,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":false,"ca_institutions":"Regional Municipality of Durham; BC Cancer Agency; University of British Columbia","funders":"","keywords":"Medicine; Loss of heterozygosity; Germline; Prostate cancer; Prostate; Oncology; DNA repair; Internal medicine; Cancer; Cancer research; Gynecology; DNA; Genetics; Allele; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002105881,0.0001515326,0.0003791815,0.00009915604,0.0001052923,0.00001273342,0.00009631498,0.00002450099,0.00003962565],"category_scores_gemma":[0.00006997169,0.0001001454,0.00007859298,0.00003506379,0.0003504101,0.00004196112,0.0001394877,0.0001094656,0.00001665887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008380966,"about_ca_system_score_gemma":0.0000656468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003579088,"about_ca_topic_score_gemma":0.0001382862,"domain_scores_codex":[0.9988856,0.0001285077,0.0002454483,0.0003254714,0.0001170317,0.0002979606],"domain_scores_gemma":[0.999181,0.00003806287,0.000131089,0.000495206,0.00004984763,0.0001047656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008546669,0.00034419,0.9910229,0.00005427672,0.0000986857,0.001851199,0.0005374125,0.000004768204,0.001313843,0.00002885086,0.00006410421,0.003825064],"study_design_scores_gemma":[0.005134805,0.001449525,0.9875618,0.00002253679,0.00006478121,0.00006449331,0.00001674618,0.00007759171,0.0009781471,0.00001189765,0.00453869,0.00007898916],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991202,0.00108417,7.712796e-7,0.003856655,0.0001140745,0.0004672377,0.00003802831,0.00003086993,0.0032062],"genre_scores_gemma":[0.9963362,0.0008604215,0.00004333674,0.0002068447,0.00004364916,0.00002422643,0.00001103258,0.00002240052,0.002451872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005134223,"threshold_uncertainty_score":0.4083811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03292710841914352,"score_gpt":0.3384234655512099,"score_spread":0.3054963571320664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}