{"id":"W2593211024","doi":"10.1158/2326-6074.tumimm16-a51","title":"Abstract A51: Early-life infection delays B cell precursor leukemia onset in Eu-Ret mice via an IL-23-dependent depletion of leukemia-initiating cells","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Leukemia; Medicine; Immunology; Epidemiology; Population; Disease; In utero; Internal medicine; Cancer research; Biology; Pregnancy; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003086895,0.0007731778,0.0003814582,0.0008750924,0.000264947,0.0005182304,0.0005999554,0.0009351884,0.003320972],"category_scores_gemma":[0.000236357,0.0003826192,0.000462466,0.0002081334,0.0006924919,0.000416902,0.0003436407,0.002036926,0.001088724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004696731,"about_ca_system_score_gemma":0.000231163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007778462,"about_ca_topic_score_gemma":0.001377438,"domain_scores_codex":[0.9994408,0.0001003815,0.00006977926,0.0001414191,0.0001113898,0.0001360771],"domain_scores_gemma":[0.9992914,0.00009158134,0.0002754483,0.00006899849,0.00003704256,0.0002354828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002641043,0.00008104904,0.0001440109,0.00002354095,0.000004076721,0.00007508918,0.00001567261,0.00004387145,0.9985989,0.00009996849,0.000041168,0.0006085911],"study_design_scores_gemma":[0.00007502435,0.001673803,0.006064142,0.0000233165,0.00002584566,0.0003498644,0.00006618819,0.0008596054,0.9885911,0.00007594173,0.002181852,0.00001326693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921045,0.0008221387,0.002670876,0.0002532765,0.00005927075,0.00006867926,0.001544838,0.0003587297,0.00211765],"genre_scores_gemma":[0.985709,0.0005023286,0.003567395,0.0001563238,0.00003094013,0.0001373432,0.0009334212,0.0001310567,0.008832352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003320972,"threshold_uncertainty_score":0.01110971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05886984749239877,"score_gpt":0.3739241100159753,"score_spread":0.3150542625235765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}