{"id":"W2593228124","doi":"10.1021/acs.biochem.7b00020","title":"Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute on Drug Abuse; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; National Science Foundation","keywords":"Chemistry; Antiparallel (mathematics); Dimer; Mass spectrometry; Hydrogen–deuterium exchange; Protein quaternary structure; Stoichiometry; Glycan; Linker; Trimer; Royal jelly; Protein structure; Crystallography; Biophysics; Biochemistry; Chromatography; Biology; Protein subunit; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005623476,0.0001137944,0.0001509309,0.000002861786,0.000237231,0.0001461842,0.0002515427,0.00006381844,0.0001495306],"category_scores_gemma":[0.00005658313,0.00004331557,0.00003364322,0.00006221566,0.0002300339,0.00006693961,0.0001465087,0.00009345887,5.521612e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008217266,"about_ca_system_score_gemma":0.000002813507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008413153,"about_ca_topic_score_gemma":0.000002313514,"domain_scores_codex":[0.9993088,0.00001319772,0.0001387495,0.0002694809,0.0001304059,0.000139351],"domain_scores_gemma":[0.9996071,0.00002796221,0.0001642954,0.0001183942,0.00002708691,0.00005520296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001140682,0.00001597052,0.002650584,0.00002640723,0.00002248319,3.486366e-7,0.000008310548,6.98299e-9,0.9935487,0.0000105223,0.0000581713,0.003647089],"study_design_scores_gemma":[0.00007512461,0.00002337548,0.02288458,0.00001441813,0.00001888718,0.000001457781,0.00005174084,0.00002200098,0.9764583,0.0001291888,0.0002208051,0.0001000847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959812,0.0001168134,0.000001904811,0.003408217,0.0000109349,0.0001009138,0.0003019968,0.00001006027,0.00006797336],"genre_scores_gemma":[0.9991935,0.00001118534,0.0001981867,0.00005459982,0.0001972642,0.000003007055,0.0001989753,0.000001002824,0.0001423085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02023399,"threshold_uncertainty_score":0.1824613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022525883539567,"score_gpt":0.2039429403963164,"score_spread":0.1937176815609207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}