{"id":"W2593228124","doi":"10.1021/acs.biochem.7b00020","title":"Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute on Drug Abuse; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Natural Sciences and Engineering Research Council of Canada; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; National Science Foundation","keywords":"Chemistry; Antiparallel (mathematics); Dimer; Mass spectrometry; Hydrogen–deuterium exchange; Protein quaternary structure; Stoichiometry; Glycan; Linker; Trimer; Royal jelly; Protein structure; Crystallography; Biophysics; Biochemistry; Chromatography; Biology; Protein subunit; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002314243,0.0003322658,0.0001527283,0.0002185773,0.0002049102,0.0003470664,0.0002394199,0.0003559059,0.000455859],"category_scores_gemma":[0.000327623,0.000170137,0.0002760368,0.0001609112,0.0002263592,0.0003222275,0.0001953416,0.0007198557,0.0002309392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362981,"about_ca_system_score_gemma":0.0001291441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004931843,"about_ca_topic_score_gemma":0.0006334701,"domain_scores_codex":[0.9998296,0.00001971976,0.0000156164,0.00006082987,0.00004801619,0.00002618005],"domain_scores_gemma":[0.9997593,0.00004455034,0.0001029726,0.00002285007,0.00002930394,0.00004105218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002688851,0.00001097029,0.0003416923,0.00001105212,0.000003299635,0.00001325721,0.00002052342,0.00002444566,0.9991419,0.00003368627,0.00001465496,0.0003575422],"study_design_scores_gemma":[0.00001018294,0.0001208177,0.02422998,0.000005895558,0.00001925095,0.0003775612,0.00008336034,0.003338458,0.9701118,0.00007151414,0.001620684,0.00001057991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955133,0.0004840734,0.003254627,0.00009488107,0.00001240113,0.00001144897,0.0001909009,0.00002953736,0.0004090028],"genre_scores_gemma":[0.9854587,0.0006178925,0.01127218,0.0001312316,0.0000160501,0.00003395762,0.001174981,0.00003301357,0.001261925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004931843,"threshold_uncertainty_score":0.002440095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022525883539567,"score_gpt":0.2039429403963164,"score_spread":0.1937176815609207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}