{"id":"W2593282276","doi":"10.1038/ncomms14774","title":"Genetic correlation between amyotrophic lateral sclerosis and schizophrenia","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Economic and Social Research Council; Medical Research Council; Centre hospitalier régional universitaire de Lille; National Institute of Mental Health; KU Leuven; Ministero dell’Istruzione, dell’Università e della Ricerca; Erasmus Medisch Centrum; ZonMw; National Institutes of Health; Rosetrees Trust; King's College London; Hjartavernd; Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease; E-Rare; Science Foundation Ireland; National Institute on Aging; National Institute for Health and Care Research; Health Research Board; Bundesministerium für Bildung und Forschung; Lundbeckfonden; Institut National de la Santé et de la Recherche Médicale; EU Joint Programme – Neurodegenerative Disease Research; Parkinson's UK; Motor Neurone Disease Association; South London and Maudsley NHS Foundation Trust; Agence Nationale de la Recherche; Wellcome Trust; ALS Association; Alzheimer's Association","keywords":"Amyotrophic lateral sclerosis; Schizophrenia (object-oriented programming); Correlation; Medicine; Genetics; Biology; Neuroscience; Psychiatry; Disease; Pathology; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00121704,0.000288528,0.0002833579,0.001323264,0.0004920939,0.0004753536,0.0003215818,0.0003892612,0.002982937],"category_scores_gemma":[0.004170975,0.000222818,0.0004088934,0.001171047,0.0005312415,0.0001944481,0.0005268162,0.0004572285,0.0002160124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002712516,"about_ca_system_score_gemma":0.0004237292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003483315,"about_ca_topic_score_gemma":0.00391326,"domain_scores_codex":[0.9989657,0.0003978845,0.000103579,0.0002290295,0.0002381248,0.00006551751],"domain_scores_gemma":[0.9965031,0.00134603,0.001444892,0.0002029006,0.0002097028,0.000293385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002753988,0.00002786678,0.9927746,0.00001832033,0.0003270145,0.0004726051,0.0000784861,0.000371907,0.003599193,0.0001896418,0.0001137312,0.001751206],"study_design_scores_gemma":[0.00001332826,0.00006619388,0.99629,0.00001313773,0.0000952613,0.0009939395,0.00009438603,0.001203989,0.0005211927,0.0005245086,0.0001742181,0.000009789106],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985911,0.0002133391,0.0005042905,0.0001196407,0.000006906842,0.00000395239,0.0002002626,0.00001212057,0.0003483517],"genre_scores_gemma":[0.9994106,0.0000689228,0.0003004438,0.00001381914,0.000006587082,0.000002415663,0.0001148107,0.000002123459,0.00008026576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003483315,"threshold_uncertainty_score":0.00997895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02703007726322525,"score_gpt":0.2955422736204225,"score_spread":0.2685121963571973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}