{"id":"W2593282276","doi":"10.1038/ncomms14774","title":"Genetic correlation between amyotrophic lateral sclerosis and schizophrenia","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Economic and Social Research Council; Medical Research Council; Centre hospitalier régional universitaire de Lille; National Institute of Mental Health; KU Leuven; Ministero dell’Istruzione, dell’Università e della Ricerca; Erasmus Medisch Centrum; ZonMw; National Institutes of Health; Rosetrees Trust; King's College London; Hjartavernd; Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease; E-Rare; Science Foundation Ireland; National Institute on Aging; National Institute for Health and Care Research; Health Research Board; Bundesministerium für Bildung und Forschung; Lundbeckfonden; Institut National de la Santé et de la Recherche Médicale; EU Joint Programme – Neurodegenerative Disease Research; Parkinson's UK; Motor Neurone Disease Association; South London and Maudsley NHS Foundation Trust; Agence Nationale de la Recherche; Wellcome Trust; ALS Association; Alzheimer's Association","keywords":"Amyotrophic lateral sclerosis; Schizophrenia (object-oriented programming); Correlation; Medicine; Genetics; Biology; Neuroscience; Psychiatry; Disease; Pathology; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001784645,0.0001047155,0.0001310228,0.00003257539,0.0008808058,0.00006328295,0.0005802302,0.0004062255,0.000004306711],"category_scores_gemma":[0.000402288,0.0001046012,0.00004950297,0.00002947267,0.0002160995,0.000006021168,0.0005270598,0.0003308176,0.00001128762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001089386,"about_ca_system_score_gemma":0.00003161298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005337636,"about_ca_topic_score_gemma":0.0003161576,"domain_scores_codex":[0.999282,0.0001180878,0.0001811688,0.0002087009,0.00005773264,0.000152278],"domain_scores_gemma":[0.9978678,0.00004566737,0.0001919525,0.001736892,0.00009375092,0.00006390985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000008439944,0.00001819179,0.9852847,0.000002308484,0.00005465929,1.398984e-7,0.00002146533,0.00001618178,0.005879378,0.0007028792,0.001643447,0.006368209],"study_design_scores_gemma":[0.0003116429,0.00003951053,0.9894255,0.000007750346,0.00003403036,0.000003565721,0.000005379709,0.0003222873,0.00009456319,0.0005970854,0.009046172,0.0001124739],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906864,0.003947486,0.0004916403,0.003394982,0.0001160439,0.0001324088,0.00003618168,0.0000128823,0.001181992],"genre_scores_gemma":[0.9830344,0.002030729,0.01417398,0.0001870712,0.0001791128,0.00002185828,0.0001854944,0.00001372229,0.0001735831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01368233,"threshold_uncertainty_score":0.6774535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02703007726322525,"score_gpt":0.2955422736204225,"score_spread":0.2685121963571973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}