{"id":"W2593287697","doi":"10.1200/jco.2013.31.15_suppl.tps2622","title":"Phase II, multicenter, open-label, proof of concept study of tasquinimod in patients with advanced/metastatic hepatocellular (HCC), ovarian (OC), renal cell (RCC) and gastric (GC) carcinomas.","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Internal medicine; Oncology; Combination therapy; Progression-free survival; Clinical endpoint; Phases of clinical research; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003887153,0.001705573,0.002214176,0.0004867823,0.0003861192,0.001023296,0.0009820912,0.001303945,0.003261989],"category_scores_gemma":[0.001442791,0.0007256569,0.00148843,0.0004847458,0.001302114,0.001097254,0.0004326713,0.002991362,0.0007527992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001075476,"about_ca_system_score_gemma":0.002335523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005560414,"about_ca_topic_score_gemma":0.001512563,"domain_scores_codex":[0.9992723,0.0003329716,0.00003169428,0.0001580824,0.00007935173,0.000125645],"domain_scores_gemma":[0.9989385,0.00015505,0.0002262474,0.0001089992,0.0001203383,0.0004508323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7674805,0.09860063,0.007192439,0.0009894656,0.001832848,0.000169526,0.0003932776,0.002634875,0.06363543,0.0004441596,0.003651579,0.05297523],"study_design_scores_gemma":[0.4398699,0.5451427,0.007045683,0.0000219623,0.0005022303,0.0001484113,0.00007717699,0.001169717,0.003728907,0.0002395091,0.002023196,0.00003056189],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831481,0.001688331,0.002160572,0.0005015128,0.0002854137,0.009239115,0.001559987,0.0001310718,0.001285877],"genre_scores_gemma":[0.9745915,0.001250328,0.006808752,0.001177094,0.0002349824,0.01142568,0.002019207,0.00004109721,0.002451326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003887153,"threshold_uncertainty_score":0.02055746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1109235187220886,"score_gpt":0.4580474076056311,"score_spread":0.3471238888835425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}