{"id":"W2593362567","doi":"10.1155/2017/6468309","title":"The Efficacy and Safety of 12 Weeks of Sofosbuvir and Ledipasvir versus Sofosbuvir, Ledipasvir, and Ribavirin in Patients with Chronic Hepatitis C, Genotype 1, Who Have Cirrhosis and Have Failed Prior Therapy: A Systematic Review and Meta-Analysis","year":2017,"lang":"en","type":"review","venue":"Canadian Journal of Gastroenterology and Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre; University of Calgary","funders":"","keywords":"Medicine; Ledipasvir; Sofosbuvir; Internal medicine; Ribavirin; Cirrhosis; Gastroenterology; Adverse effect; Randomized controlled trial; Hepatitis C; Surgery; Chronic hepatitis; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01099371,0.002359893,0.01906189,0.005801063,0.0005576621,0.002772468,0.002148924,0.002304567,0.00258192],"category_scores_gemma":[0.02184354,0.001594752,0.03284638,0.005912747,0.0008197066,0.001475026,0.001341889,0.001600391,0.0002720438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003303495,"about_ca_system_score_gemma":0.003840341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006813609,"about_ca_topic_score_gemma":0.01639053,"domain_scores_codex":[0.9925624,0.003233405,0.00244244,0.0007221604,0.0008117722,0.0002278187],"domain_scores_gemma":[0.9874628,0.008150457,0.002862213,0.0003184548,0.000961046,0.000245032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003767655,0.00003647283,0.002586487,0.3971928,0.586629,0.0001242591,0.00008295134,0.0004498168,0.000271497,0.00008482832,0.0004111515,0.008363142],"study_design_scores_gemma":[0.001048373,0.0002803798,0.00225967,0.02027943,0.9747393,0.00008274901,0.00003375516,0.0001603871,0.0001058367,0.0001067359,0.0008831176,0.00002036563],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009463247,0.9886906,0.0003746722,0.0001990345,0.0001276266,0.0003746708,0.0005089772,0.00002437265,0.000236683],"genre_scores_gemma":[0.2661143,0.7280677,0.001850401,0.00112203,0.0002190696,0.001355662,0.0008190425,0.00003036679,0.0004213511],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01906189,"threshold_uncertainty_score":0.05814093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06832065232720909,"score_gpt":0.3348983230871413,"score_spread":0.2665776707599322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}