{"id":"W2593434335","doi":"10.1159/000464386","title":"RASSF10 is Epigenetically Inactivated and Suppresses Cell Proliferation and Induces Cell Apoptosis by Activating the p53 Signalling Pathway in Papillary Thyroid Carcinoma Cancer","year":2017,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Apoptosis; Transfection; Cell growth; Cell culture; Cancer research; Flow cytometry; Cell; Biology; DNA methylation; Methylation; Chemistry; Cell biology; Molecular biology; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001707076,0.0002275814,0.0001940837,0.00001827475,0.0004357624,0.00008618736,0.0001710868,0.0003578542,0.000007719322],"category_scores_gemma":[0.000053906,0.0001829518,0.00003151004,0.00003317495,0.0002953177,0.0000128867,0.0002194845,0.0002053911,2.396821e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008941743,"about_ca_system_score_gemma":0.00006028857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007505208,"about_ca_topic_score_gemma":0.000004249085,"domain_scores_codex":[0.9988413,0.0000823594,0.0002115461,0.0005366354,0.0000795587,0.0002485881],"domain_scores_gemma":[0.9992988,0.0000454015,0.000201009,0.0003142804,0.00006244533,0.00007803095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005513729,0.0000388039,0.01354237,0.0001093217,0.00001678297,7.226043e-7,0.0001257102,0.000004437138,0.9847481,0.000001357617,0.00003568234,0.001321612],"study_design_scores_gemma":[0.0004750862,0.0001105942,0.006975793,0.00002061804,0.00001429032,8.178953e-7,0.0001361254,0.0001340083,0.9915997,0.0001114132,0.0001891445,0.0002323909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865995,0.01270911,0.00004883513,0.0002430597,0.00004056053,0.0001832728,0.00003190269,0.00000485502,0.0001389171],"genre_scores_gemma":[0.9957153,0.00363033,0.00006832153,0.00008954601,0.000179982,0.0000385319,0.0001195306,0.00001914608,0.0001393331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009115792,"threshold_uncertainty_score":0.7460558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008598942607981781,"score_gpt":0.2274988232701447,"score_spread":0.2188998806621629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}