{"id":"W2593440173","doi":"10.1038/labinvest.2017.10","title":"Antibodies against nonstructural protein 1 protect mice from dengue virus-induced mast cell activation","year":2017,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Ministry of Science and Technology, Taiwan","keywords":"Degranulation; Dengue virus; Tryptase; Chemokine; Chymase; Mast cell; Proinflammatory cytokine; Dengue fever; Antibody; Immunology; Biology; Immunoglobulin E; Histamine; Inflammation; Virology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005081808,0.001706871,0.0006262694,0.00111707,0.0004032387,0.0005060886,0.0005657516,0.001189884,0.002303282],"category_scores_gemma":[0.0004347119,0.0005810257,0.000534419,0.0001925109,0.0008237617,0.000818981,0.00030422,0.003076877,0.0006401361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004917572,"about_ca_system_score_gemma":0.0003818286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005616302,"about_ca_topic_score_gemma":0.000981956,"domain_scores_codex":[0.9995781,0.00007113042,0.00002814989,0.00008326313,0.00007038854,0.0001690512],"domain_scores_gemma":[0.9993019,0.00009868271,0.0002314644,0.00008683292,0.00005077509,0.0002303835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004174861,0.001016848,0.000918561,0.00007781891,0.00003093442,0.0001675412,0.00007908027,0.000196958,0.9901018,0.0003324648,0.000267433,0.002635716],"study_design_scores_gemma":[0.001287793,0.01099168,0.01406566,0.00005792105,0.0001513123,0.000676269,0.0002087437,0.002256528,0.9671041,0.0006386065,0.002527771,0.00003373354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957385,0.0008218815,0.001261286,0.0003141905,0.0001541059,0.00006758159,0.0003163007,0.0001600243,0.001166232],"genre_scores_gemma":[0.9922667,0.000843231,0.001283368,0.0002468464,0.00008313404,0.0001178325,0.0005287293,0.00004961439,0.004580537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002303282,"threshold_uncertainty_score":0.007705212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01678837186711234,"score_gpt":0.2513907036225145,"score_spread":0.2346023317554022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}