{"id":"W2593530729","doi":"10.1182/blood.v108.11.684.684","title":"Rapid and Irreversible Alteration of the Ability of Hematopoietic Stem Cells To Execute Both Symmetric and Asymmetric Self-Renewal Divisions by Exposure to Reduced Steel Factor Concentrations with No Effect on Their Survival or Mitogenesis.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Haematopoiesis; Bone marrow; Stem cell; Biology; Population; Transplantation; Stromal cell; Myeloid; Immunology; Cell biology; Andrology; Molecular biology; Chemistry; Internal medicine; Cancer research; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369674,0.0003263213,0.0001523984,0.0001155269,0.00007074322,0.0001424233,0.0001956865,0.0001725289,0.001490366],"category_scores_gemma":[0.0001008452,0.0001190038,0.0001866273,0.00007192539,0.0001429834,0.00009800441,0.0001396477,0.0004372269,0.0003430262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001608741,"about_ca_system_score_gemma":0.000137207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004936887,"about_ca_topic_score_gemma":0.0008644377,"domain_scores_codex":[0.9998597,0.00002556455,0.00001407356,0.00002366647,0.00004133485,0.00003568293],"domain_scores_gemma":[0.9999062,0.00001971743,0.00002023819,0.00002046385,0.0000113953,0.00002187914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000745728,0.00001436581,0.00008199497,0.00001363183,0.000002445325,0.00001114145,0.00000640469,0.00001981682,0.9990496,0.00003251444,0.00002416856,0.0006693405],"study_design_scores_gemma":[0.000011599,0.0005503999,0.004934951,0.000004483489,0.00000649953,0.00007587326,0.00001278771,0.0003136721,0.9926214,0.0000150866,0.00145021,0.000002925179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943387,0.001014825,0.001973857,0.00005129039,0.00002958043,0.00004101889,0.0005839662,0.0000801563,0.001886609],"genre_scores_gemma":[0.9939481,0.0004086511,0.001638155,0.00003954722,0.000008748864,0.00005721175,0.00105415,0.00001687546,0.002828558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001490366,"threshold_uncertainty_score":0.00498575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01071556015608005,"score_gpt":0.223564535857026,"score_spread":0.212848975700946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}