{"id":"W2593652139","doi":"10.1371/journal.ppat.1006250","title":"Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine","year":2017,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"Secretaría de Estado de Investigación, Desarrollo e Innovación; Alberta Glycomics Centre; Universidad de Antioquia; Ikerbasque, Basque Foundation for Science; Aeras Global Tuberculosis Vaccine Foundation; National Cancer Institute; National Institutes of Health; Ministerio de Economía y Competitividad; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Immunogenicity; Mycobacterium tuberculosis; Antibody; Tuberculosis; Tuberculosis vaccines; Immunology; Immunity; Conjugate vaccine; Biology; Immunization; Virology; Antigen; Humoral immunity; Conjugate; Microbiology; Immune system; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006268313,0.0002467735,0.0007679809,0.0001757714,0.0001357478,0.00002322369,0.0002924192,0.0002203352,0.0001581095],"category_scores_gemma":[0.001435919,0.0002174715,0.0001365507,0.00009621323,0.0001178568,0.0002943501,0.00006314786,0.0003063885,0.00003356671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007788789,"about_ca_system_score_gemma":0.00005168603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002180705,"about_ca_topic_score_gemma":0.0000942031,"domain_scores_codex":[0.9977383,0.0002804853,0.000613276,0.0005126058,0.0002909106,0.000564429],"domain_scores_gemma":[0.9982384,0.0001621424,0.0002986124,0.0007660077,0.0002216483,0.0003131472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009068954,0.0007353132,0.05508759,0.0001769775,0.00009467281,0.00007699409,0.0001335311,0.000001616764,0.9388826,0.00003809524,0.0002521984,0.003613512],"study_design_scores_gemma":[0.002147226,0.000807066,0.4825825,0.0003004758,0.00009709882,0.00001766795,0.00007171887,0.002784977,0.5108042,0.00007823926,0.0001005463,0.0002082355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936656,0.0004409042,0.0002535141,0.003434849,0.00005587857,0.0009045376,0.0002811345,0.00003733062,0.0009263009],"genre_scores_gemma":[0.9984263,0.000288947,0.0002264732,0.0002147065,0.0001174022,0.0001919595,0.0002282504,0.00003740855,0.0002686014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4280784,"threshold_uncertainty_score":0.8868232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01826736632392498,"score_gpt":0.3059385847899941,"score_spread":0.2876712184660691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}