{"id":"W2593830421","doi":"10.1038/srep44134","title":"Size matters for in vitro gene delivery: investigating the relationships among complexation protocol, transfection medium, size and sedimentation","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Transfection; Sedimentation; In vitro; Gene delivery; Protocol (science); Gene; Computational biology; Chemistry; Biology; Genetics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001175437,0.00009114711,0.00008039406,0.0000297523,0.0008228392,0.000287402,0.00009958823,0.00007145511,0.000004853461],"category_scores_gemma":[0.0005312899,0.00007463267,0.00004213543,0.00004809484,0.000287846,0.00003752399,0.00003755949,0.00006888762,7.263137e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001733406,"about_ca_system_score_gemma":0.00006331976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001200085,"about_ca_topic_score_gemma":0.0004123932,"domain_scores_codex":[0.9989692,0.00006447505,0.000289265,0.0003983588,0.0001387166,0.0001400091],"domain_scores_gemma":[0.9991095,0.00005201657,0.0002857391,0.0004040803,0.0001068162,0.00004182311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000355361,0.00001196502,0.02027103,0.00001835721,0.000008676376,0.000001936015,0.0002017196,0.00004755419,0.9778905,0.000002406464,0.001018378,0.0004919236],"study_design_scores_gemma":[0.0003435455,0.00004663436,0.1543877,0.00002480145,0.00001252305,0.00001936235,0.0001492737,0.0003156179,0.8420202,0.001053344,0.001526427,0.0001005284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903291,0.000008411416,0.0006808442,0.000614098,0.0005882976,0.007708007,0.000004331292,0.00000705126,0.00005985394],"genre_scores_gemma":[0.9932581,0.000001336447,0.001107689,0.00009667833,0.00007942559,0.005093208,0.00008561534,0.0000088147,0.0002691526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1358703,"threshold_uncertainty_score":0.6328697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03418929487461972,"score_gpt":0.286767234510107,"score_spread":0.2525779396354874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}