{"id":"W2593872179","doi":"10.1128/mbio.00140-17","title":"New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions","year":2017,"lang":"en","type":"article","venue":"mBio","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Host (biology); Microbiology; Gram-negative bacteria; Bacteria; Biology; Escherichia coli; Ecology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009732038,0.0001661669,0.0002672023,0.00005315329,0.001150801,0.00009562662,0.0001930258,0.00009056587,0.00004967913],"category_scores_gemma":[0.0001160985,0.0001259813,0.00007635598,0.00003151585,0.0002736849,0.0002741576,0.0001665291,0.0002316832,0.0000106525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004206501,"about_ca_system_score_gemma":0.00007141135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001933417,"about_ca_topic_score_gemma":0.001273963,"domain_scores_codex":[0.9992602,0.00005934694,0.0001954455,0.0002457329,0.00001480748,0.0002244436],"domain_scores_gemma":[0.9990658,0.0002376034,0.0002577169,0.0003441633,0.0000769274,0.00001781827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007462526,0.0004463582,0.001204739,0.00001186597,0.0003370148,1.102565e-7,0.003238971,0.00004468046,0.9889148,0.0000929729,0.004354844,0.001278971],"study_design_scores_gemma":[0.006664318,0.001532666,0.01750739,0.0000801995,0.0003315012,0.00002026864,0.002949037,0.0002751134,0.9654903,0.0001625938,0.004564543,0.0004220899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948683,0.000109569,0.003379043,0.0002006345,0.0003266981,0.0008043628,0.0001955456,0.00003201966,0.00008378243],"genre_scores_gemma":[0.9953155,0.00007174166,0.00006821773,0.00002939983,0.00004601518,0.00003327709,0.00002130333,0.0000183334,0.004396218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02342457,"threshold_uncertainty_score":0.8851144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02017157773058065,"score_gpt":0.2789108671944377,"score_spread":0.258739289463857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}