{"id":"W2594087813","doi":"10.1182/blood.v128.22.222.222","title":"Health-Related Quality of Life (HRQoL) of Blinatumomab Versus Standard of Care (SOC) Chemotherapy in Patients with Relaspsed or Refractory Philadelphia Negative B-Cell Precursor Acute Lymphoblastic Leukemia in a Randomized, Open-Label Phase 3 Study (TOWER)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Blinatumomab; Medicine; Internal medicine; Acute lymphocytic leukemia; Oncology; Chemotherapy; Leukemia; Lymphoblastic Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001937896,0.000482007,0.003664213,0.000616079,0.00004368479,0.00001094403,0.0005984803,0.0002784114,0.00010132],"category_scores_gemma":[0.003269444,0.0002966552,0.0001418259,0.001240236,0.0006292309,0.0002594551,0.0002330792,0.0004064197,0.000003062768],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002795297,"about_ca_system_score_gemma":0.009677698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001427175,"about_ca_topic_score_gemma":0.0005357313,"domain_scores_codex":[0.9932312,0.001247474,0.00262609,0.0007584185,0.001506702,0.0006300666],"domain_scores_gemma":[0.992669,0.003207155,0.001833399,0.0008976841,0.001054608,0.0003380893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9553991,0.01985959,0.01158799,0.000746334,0.001482092,0.00006261301,0.008602015,0.000005421425,0.001170232,0.00001195509,0.0001133702,0.0009593206],"study_design_scores_gemma":[0.9341387,0.04707108,0.008303655,0.001683888,0.0004446522,0.000002547642,0.001653116,0.00006039909,0.006325328,0.0000179188,0.000004930524,0.0002937721],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911866,0.000404844,0.00004612972,0.0003054769,0.00008617082,0.007275025,0.0004588951,0.00002760868,0.0002092302],"genre_scores_gemma":[0.9985805,0.0001924928,0.0007346178,0.0000427637,0.0000167634,0.0002052277,0.00004341641,0.0000886081,0.00009560671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02721149,"threshold_uncertainty_score":0.9999486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02880408229329576,"score_gpt":0.3432432151383191,"score_spread":0.3144391328450233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}