{"id":"W2594087813","doi":"10.1182/blood.v128.22.222.222","title":"Health-Related Quality of Life (HRQoL) of Blinatumomab Versus Standard of Care (SOC) Chemotherapy in Patients with Relaspsed or Refractory Philadelphia Negative B-Cell Precursor Acute Lymphoblastic Leukemia in a Randomized, Open-Label Phase 3 Study (TOWER)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Blinatumomab; Medicine; Internal medicine; Acute lymphocytic leukemia; Oncology; Chemotherapy; Leukemia; Lymphoblastic Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00179347,0.00109466,0.002014475,0.0003751706,0.0003717365,0.0007173284,0.0005605371,0.0008804041,0.003133586],"category_scores_gemma":[0.0009875068,0.0004959343,0.00215548,0.00039593,0.0008479907,0.000711843,0.0004166231,0.001898116,0.0003229573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001116237,"about_ca_system_score_gemma":0.001054805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007491098,"about_ca_topic_score_gemma":0.002033763,"domain_scores_codex":[0.9991131,0.0005199485,0.00005683124,0.0001143216,0.00008022526,0.0001154277],"domain_scores_gemma":[0.9990833,0.0001890232,0.0002968177,0.00005444741,0.00004935557,0.0003271103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9653896,0.01217211,0.004889124,0.0003235113,0.0009397386,0.00002649269,0.00004896822,0.0004758686,0.003760641,0.00004009467,0.0003757046,0.01155813],"study_design_scores_gemma":[0.5139978,0.4609813,0.0214899,0.00003216908,0.0008655066,0.00005243539,0.00003865285,0.0006130011,0.00129788,0.00006962311,0.000538741,0.00002313168],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972778,0.00095376,0.0001126506,0.0001160009,0.00005399142,0.0007406725,0.0004321965,0.00001261434,0.0003003501],"genre_scores_gemma":[0.9967337,0.000459883,0.0004166828,0.0002278023,0.0000937304,0.001194834,0.0005095191,0.000003337727,0.0003605165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003133586,"threshold_uncertainty_score":0.01048291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02880408229329576,"score_gpt":0.3432432151383191,"score_spread":0.3144391328450233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}